Mitochondrial respiratory capacity, sperm motility linked

April 10, 2012
Mitochondrial respiratory capacity, sperm motility linked
Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology.

(HealthDay) -- Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology.

Alessandra Ferramosca, of the University of Salento in Lecce, Italy, and colleagues investigated whether sperm mitochondrial respiratory efficiency correlated with and sperm morphologic anomalies. They used a polarographic assay of to evaluate the mitochondrial respiratory activity of hypotonically-treated .

The researchers observed a positive correlation between mitochondrial respiratory efficiency and sperm motility and a negative correlation with the percentage of immotile sperm. Mitochondrial functionality was impaired in sperm with midpiece defects.

"The results reported in this study support a strong and positive correlation between mitochondrial respiratory efficiency and sperm progressive motility. In addition and in strict agreement with these findings, morphologic alterations of the sperm midpiece, where mitochondria are found, are associated with lower mitochondrial functionality and lower sperm motility," the authors write. "These results confirm the important role played by mitochondria in supplying for sperm motility and provide more insights into the biochemical basis of mitochondria-based asthenozoospermia."

Explore further: Study: Cell phones reduce sperm counts

More information: Abstract
Full Text (subscription or payment may be required)


Related Stories

Study: Cell phones reduce sperm counts

October 24, 2006

A study debuted in New Orleans has suggested that electromagnetic radiation from cell phones may have an effect on a man's sperm count.

Viagra could be harmful to fertility

February 25, 2008

A study to be published in the British medical journal Fertility and Sterility suggests that Viagra could harm men's fertility.

Taiwan scientists develop sperm 'efficiency' kit

September 17, 2009

Scientists in Taiwan said Thursday they have invented a male fertility home test kit that breaks new ground by measuring the efficiency of sperm cells -- a key factor in determining men's ability to father children.

Researchers Develop Test to Identify 'Best' Sperm

May 20, 2010

(PhysOrg.com) -- Researchers at Yale School of Medicine have discovered a method to select sperm with the highest DNA integrity in a bid to improve male fertility. The method is comparable to that of the egg’s natural selection ...

Overweight men have poorer sperm count

July 4, 2011

Overweight or obese men, like their female counterparts, have a lower chance of becoming a parent, according to a comparison of sperm quality presented at a European fertility meeting Monday.

Recommended for you

Sustaining biomedical research: Med school deans speak out

May 27, 2015

Cuts in federal support and unreliable funding streams are creating a hostile work environment for scientists, jeopardizing the future of research efforts and ultimately clinical medicine, according to leaders of the nation's ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.