Patient-centered approach key for T2DM management

Silvio E. Inzucchi, M.D., from the Yale University School of Medicine in Haven Hospital, Conn., and colleagues reviewed the literature and examined the evidence to develop recommendations for antihyperglycemic therapy in nonpregnant adults with type 2 diabetes.

The authors recommend that glycemic targets and glucose-lowering therapies should be individualized for each patient. Diet, exercise, and education are still the basis of any treatment program for type 2 diabetes, and resources should be made available. Metformin should be the first-line therapy for hyperglycemia, unless there are prevalent contraindications. Data are limited for subsequent therapies; combination of an additional one to two oral or injectable agents is reasonable, with emphasis on minimizing side effects. Ultimately, a substantial proportion of patients will require insulin treatment, either alone or in combination with other agents. Where possible, treatment decisions should be made in conjunction with the patients, focusing on specific needs, preferences, and values. A major focus of therapy should be reduction of cardiovascular risk.

"These recommendations should be considered within the context of the needs, preferences, and tolerances of each patient; individualization of treatment is the cornerstone of success," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

More information: Full Text

Copyright © 2012 HealthDay. All rights reserved.