Stanford and MIT scientists win Perl-UNC Neuroscience prize
From the left this is Karl Deisseroth, M.D., Ph.D., Edward Boyden, Ph.D. and Feng Zhang, Ph.D. Credit: Photos courtesy of Stanford and MIT.
The University of North Carolina at Chapel Hill has awarded the 12th Perl-UNC Neuroscience prize to Karl Deisseroth, MD, PhD of Stanford University and Edward Boyden, PhD and Feng Zhang, PhD of the Massachusetts Institute of Technology.
Dr. Deisseroth is associate professor of bioengineering and psychiatry at Stanford University and an HHMI Early Career Scientist. Dr. Boyden is the Benesse Career Development Professor and associate professor of biological engineering and brain and cognitive sciences at the MIT Media Lab and the MIT McGovern Institute. Dr. Zhang is an investigator at the MIT McGovern Institute and an assistant professor of neuroscience in the brain and cognitive sciences department.
The Perl prize carries a $10,000 award and is given to recognize a seminal achievement in neuroscience. Past recipients have included four subsequent winners of the Nobel Prize for Physiology and Medicine.
This year's Perl Prize is being awarded to Deisseroth, Boyden and Zhang for the "Development and application of optogenetics for studying neural circuit functions."
Working in the Deisseroth laboratory in the departments of psychiatry and bioengineering at Stanford University, Dr. Deisseroth along with Boyden and Zhang developed methods of introducing light sensitive channels derived from lower organisms, such as algae and bacteria, into neurons.
Further, they optimized techniques to stimulate these channels in genetically distinct populations of neurons of living animals by using fiber optic technologies to deliver light from a laser directly into discrete brain regions. The development of these "optogenetic" techniques has sparked a revolution in neuroscience by allowing scientists to identify groups of neurons associated with particular behaviors and to determine how the activity of groups of neurons can influence brain functions.
Optogenetic technique application has already led to major breakthroughs in learning and memory research and increased our understanding of several neurological and psychiatric disorders.
Dr. Edward R. Perl is Sarah Graham Kenan Professor of cell and molecular physiology at UNC School of Medicine. Perl's work in pain mechanisms has been highly influential. Thirty years ago, he was the first to prove that a particular class of nerve cells (now called nociceptors) responds exclusively to stimuli that are perceived as painful. These cells now are targets of intensive efforts to find drugs that block their function.
Dr. Deisseroth will visit UNC on May 14 to receive a share of the prize from William Roper, Dean of the UNC School of Medicine, and present a lecture. Drs. Boyden and Zhang will visit UNC on September 20 to receive their shares of the prize and present lectures.
Provided by University of North Carolina School of Medicine
- Controlling brain circuits with light May 03, 2011 | not rated yet | 0
- Neuroengineers silence brain cells with multiple colors of light Jan 06, 2010 | not rated yet | 0
- A 'traffic light' for neurons means 'go' for improving brain research Apr 04, 2007 | not rated yet | 0
- Researchers validate, extend fMRI research on brain activity May 16, 2010 | not rated yet | 0
- Brain works best when cells keep right rhythms Apr 26, 2009 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Why is zone 1 in liver more prone to ischemic injury?
23 hours ago Hi, Is it because around central vein, there is only deoxygenated blood from the vein where as in the periphery there is hepatic artery. Also why...
How can there be villous adenoma in colon, if there are no villi there
May 22, 2013 As title suggest. Thanks :smile:
How can there be a term called "intestinal metaplasia" of stomach
May 21, 2013 Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
- More from Physics Forums - Medical Sciences
More news stories
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
Neuroscience 10 hours ago | 4.8 / 5 (5) | 0 |
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
Neuroscience 14 hours ago | 1 / 5 (1) | 0 |
A new study determined that children and adolescents with seizures involving the temporal lobe are likely to have clinically significant behavioral problems and psychiatric illness, especially depression. Findings published ...
Neuroscience 14 hours ago | not rated yet | 0
As the human body fine-tunes its neurological wiring, nerve cells often must fix a faulty connection by amputating an axon—the "business end" of the neuron that sends electrical impulses to tissues or other ...
Neuroscience 16 hours ago | 5 / 5 (2) | 0 |
A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims.
Neuroscience 16 hours ago | not rated yet | 0 |
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
15 hours ago | 4.5 / 5 (10) | 1 |
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.
13 hours ago | 5 / 5 (1) | 2 |
Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as ...
13 hours ago | 5 / 5 (2) | 0 |
Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center ...
14 hours ago | not rated yet | 0 |
Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine.
11 hours ago | not rated yet | 0 |
By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.
12 hours ago | not rated yet | 0 |