Better understanding arthritis

Better arthritis treatment could be one step closer with research showing muscle inflammation outside joints as much to blame for discomfort and poor mobility in sufferers as inflammation of the joint itself.

Knee treatment has focussed on relieving knee but researchers from Victoria University, La Trobe University, Warringal Hospital and St Vincent’s Hospital found inflammation outside the joint in those suffering knee osteoarthritis, meaning that treatment may need changing.

Lead researchers from Victoria University Dr Pazit Levinger and Dr Itamar Levinger explained was a body’s natural reaction to injury or infection but lead to muscle wastage when prolonged. For those with this muscle wastage can result in less capacity to perform daily activities.

“With the better understanding of changes in muscle function coming out of this study we will be able to target exercise and drug therapy more effectively to keep this population active and increase their quality of life for longer,” Dr Itamar Levinger said.

The Arthritis Australia sponsored project based on previous findings published in the Arthritis and Rheumatism journal will now test healthy 55- to 80-year-olds as a control group to see how the muscle function behaves in those without knee osteoarthritis.

For this next phase researchers are seeking participants to attend Victoria University’s Footscray Park campus twice: First to assess their fitness and strength and second for a resting muscle biopsy. Blood cholesterol and sugar levels will also be tested and made available to participants.

“Those who participate in this next stage of research will learn more about their fitness level and muscle strength as well as helping us develop better treatment for those suffering knee osteoarthritis,” he said.

add to favorites email to friend print save as pdf

Related Stories

Benefits of exercise for arthritis sufferers

Mar 10, 2011

An estimated 50 million adults in the United States suffer from arthritis. According to the Centers for Disease Control and Prevention, one of the best ways to combat the onset of arthritis, control pain and improve function ...

Detecting early signs of osteoarthritis

Jul 23, 2009

Researchers at The University of Nottingham are hoping to find out if inflammation of the knee could be an early sign of osteoarthritis — a condition which leads to pain, stiffness, swelling and disability.

Recommended for you

ACR: Most hospitalizations for gout are preventable

Nov 18, 2014

(HealthDay)—Most hospitalizations for a primary diagnosis of gout are preventable, according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in ...

TNF inhibitors may increase cancer risk in the eye

Nov 17, 2014

One of the family of drugs prescribed for rheumatoid arthritis and other inflammatory conditions is called TNF inhibitors. They act by dampening part of the immune system called tumor necrosis factor (TNF). In one of the ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.