Body fat linked to reduced fracture risk for women

Body fat linked to reduced fracture risk for women
Higher body fat mass is associated with a reduced risk of fracture among women, but not men, according to a study published in the May issue of the Journal of Internal Medicine.

(HealthDay) -- Higher body fat mass is associated with a reduced risk of fracture among women, but not men, according to a study published in the May issue of the Journal of Internal Medicine.

Alireza Moayyeri, M.D., from the University of Cambridge in the United Kingdom, and colleagues examined the association between percentage body fat and the risk of hip and osteoporotic fracture for 14,789 participants (6,470 men; aged 42 to 82 years at baseline) from the European Prospective Investigation into Cancer cohort.

The researchers found that, during an average follow-up of 8.7 years, 556 participants suffered a fracture, including 184 hip fractures. Among , but not men, the risk of hip fracture decreased linearly with increasing percentage of body fat. After adjusting for confounding variables and bone density, as measured by heel broadband ultrasound attenuation (BUA), a 10 percent increased percentage of body fat correlated with a reduced risk of hip fracture (hazard ratio [HR], 0.56; 95 percent confidence interval [CI], 0.39 to 0.79 in women; and HR, 0.92; 95 percent CI, 0.39 to 2.21 in men). The effect size in women was roughly equal to a five year age difference or one standard deviation increased BUA. The association between any type of fracture and percentage of body fat was nonlinear and negative among women, but not men.

"The percentage of appears to predict risk in women with an effect size comparable to that of as measured by heel ultrasound," the authors write.

More information: DOI: 10.1111/j.1365-2796.2011.02443.x

add to favorites email to friend print save as pdf

Related Stories

Hip fracture surgery type impacts future fracture risk

Mar 17, 2012

(HealthDay) -- Patients with a primary proximal femoral fracture who undergo closed reduction and percutaneous pinning have a significantly increased risk of subsequent contralateral hip fracture compared ...

Recommended for you

Home walking program improves erectile function after MI

5 hours ago

(HealthDay)—For men with recent acute myocardial infarction, a home-based walking program is associated with a reduction in reported erectile dysfunction (ED), according to a study published in the March ...

Trapping the Ebola virus in transit

6 hours ago

The deadly Ebola virus makes use of host mechanisms – including a specific type of membrane-bound calcium channel – to gain entry into the cell cytoplasm. LMU researchers now show that blocking this channel ...

Saudi reports 10 MERS deaths in a week

6 hours ago

Ten more people in Saudi Arabia have died from MERS over the past week, health ministry figures showed on Friday, after an international mission urged extra measures to combat the virus.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.