Lower limb muscle limitations hamper walking in diabetes

May 30, 2012
Lower limb muscle limitations hamper walking in diabetes

(HealthDay) -- In older adults, diabetes correlates with slower walking speed, and diabetes-linked reductions in muscle strength and worse muscle quality contribute to these walking limitations, according to a study published online May 17 in Diabetes Care.

Stefano Volpato, M.D., M.P.H., from the University of Ferrara in Italy, and colleagues conducted a cross-sectional analysis of 835 participants (aged 65 years old and older; , 11.4 percent) enrolled in a population-based study. Peripheral quantitative was used to assess total, muscular, and fat cross-sectional areas of the calf and relative muscle density. Knee extension torque, ankle plantar flexion and dorsiflexion strength, lower extremity muscle power, and ankle muscle quality were used as indicators of muscle performance. Gait was measured by the 4-m and 400-m tests.

The researchers found that participants with diabetes had significantly lower muscle density, knee and ankle strength, and muscle power, as well as worse muscle quality, after adjustment for age and gender. Participants with diabetes were significantly slower on both the 4-m and 400-m walking tests. In the 4-m and 400-m tests, lower limb muscle characteristics accounted for 24.3 and 15.1 percent, respectively, of the difference in the walking speed between individuals with and without diabetes.

"In older persons, diabetes is associated with reduced muscle strength and worse muscle quality," the authors write.

Explore further: Older men with higher testosterone levels lose less muscle mass as they age

More information: Abstract
Full Text (subscription or payment may be required)


Related Stories

Fewer mitochondria in offspring of parents with diabetes

March 26, 2012

(HealthDay) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study published in ...

Better understanding arthritis

May 2, 2012

Better arthritis treatment could be one step closer with research showing muscle inflammation outside joints as much to blame for discomfort and poor mobility in sufferers as inflammation of the joint itself.

Increased muscle mass may lower risk of pre-diabetes

July 28, 2011

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that the greater an individual's total muscle mass, the lower the person's risk of having insulin ...

Recommended for you

Low-carb diet may aid your metabolism

December 2, 2016

(HealthDay)—Eating low-carbohydrate meals may lead to healthy changes in a woman's metabolism that don't occur when consuming higher-carbohydrate meals, a small study suggests.

Research shows nerve growth protein controls blood sugar

November 14, 2016

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.