Lower limb muscle limitations hamper walking in diabetes

May 30, 2012
Lower limb muscle limitations hamper walking in diabetes

(HealthDay) -- In older adults, diabetes correlates with slower walking speed, and diabetes-linked reductions in muscle strength and worse muscle quality contribute to these walking limitations, according to a study published online May 17 in Diabetes Care.

Stefano Volpato, M.D., M.P.H., from the University of Ferrara in Italy, and colleagues conducted a cross-sectional analysis of 835 participants (aged 65 years old and older; , 11.4 percent) enrolled in a population-based study. Peripheral quantitative was used to assess total, muscular, and fat cross-sectional areas of the calf and relative muscle density. Knee extension torque, ankle plantar flexion and dorsiflexion strength, lower extremity muscle power, and ankle muscle quality were used as indicators of muscle performance. Gait was measured by the 4-m and 400-m tests.

The researchers found that participants with diabetes had significantly lower muscle density, knee and ankle strength, and muscle power, as well as worse muscle quality, after adjustment for age and gender. Participants with diabetes were significantly slower on both the 4-m and 400-m walking tests. In the 4-m and 400-m tests, lower limb muscle characteristics accounted for 24.3 and 15.1 percent, respectively, of the difference in the walking speed between individuals with and without diabetes.

"In older persons, diabetes is associated with reduced muscle strength and worse muscle quality," the authors write.

Explore further: Reducing risk of hospitalization in the elderly

More information: Abstract
Full Text (subscription or payment may be required)


Related Stories

Reducing risk of hospitalization in the elderly

July 30, 2009

Older adults who have less strength, poor physical function and low muscle density are at higher risk of being hospitalized compared to adults with more strength and better function. That's the finding of a new study in the ...

Increased muscle mass may lower risk of pre-diabetes

July 28, 2011

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that the greater an individual's total muscle mass, the lower the person's risk of having insulin ...

Fewer mitochondria in offspring of parents with diabetes

March 26, 2012

(HealthDay) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study published in ...

Better understanding arthritis

May 2, 2012

Better arthritis treatment could be one step closer with research showing muscle inflammation outside joints as much to blame for discomfort and poor mobility in sufferers as inflammation of the joint itself.

Recommended for you

Diets avoiding dry-cooked foods can protect against diabetes

August 24, 2016

Simple changes in how we cook could go a long way towards preventing diabetes, say researchers at the Icahn School of Medicine at Mount Sinai. A new randomized controlled trial, published online July 29 in the journal Diabetologia, ...

New study reveals a novel protein linked to type 2 diabetes

August 16, 2016

Findings from Boston University School of Medicine (BUSM), which appear in eLife, provide a possible explanation as to why most people who are obese develop insulin resistance and type 2 diabetes. A minority of obese individuals, ...

Bacteria may cause type 2 diabetes

June 1, 2015

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.