When too much sun is not enough
Practicing sun avoidance is important for lupus patients
(Medical Xpress) -- Lupus patients show more severe symptoms of the disease if their vitamin D levels are low, an Australian-first study has found.
Systemic lupus erythematosus (SLE), which affects more than five million people worldwide, was found to be worse in vitamin D deficient SLE patients than in those with normal levels, in the study led by Professor Eric Morand, head of the Monash Lupus Clinic and Southern Clinical School at Monash Medical Centre.
Professor Morand said although practicing sun avoidance is important for lupus patients, as sunlight can make aspects of the disease worse, this can lead to vitamin D deficiency and an increase in the severity of the disease.
In multicultural Australia, instances of vitamin D deficiency can be seen in cultural groups where clothing covers the body, in people with dark skin tone who have lower absorption, and those who practice sun avoidance Professor Morand said.
Although its too soon to draw conclusions about the long-term safety and effectiveness of vitamin D supplements in lupus, a clinical trial is the next step proving that supplementing vitamin D makes lupus better.
For Professor Morand, the battle to find new treatments carries added significance. His sister Maxine Morand, CEO of Breast Cancer Network Australia, was diagnosed with lupus more than 20 years ago, coincidentally around the same time he started researching the disease.
Ms Morand, a former nurse and Victorian Minister, said she was just 26 when she discovered she had the autoimmune disease, meaning the body's immune system attacks itself.
As a patient with vitamin D deficiency, Im fascinated by these findings, Ms Morand said.
If it can be proved that vitamin D supplementation improves outcomes for the patient and reduces symptoms, then it could significantly improve their quality of life.
For Ms Morand, symptoms include bouts of extreme tiredness, hair loss, skin rashes and sun-intolerance.
The findings will be presented at the Annual Scientific Meeting of the Australian Rheumatology Association in Canberra from 11 to 15 May, coinciding with the observance of World Lupus Day on 10 May.
The research involved five years of clinical data and blood sample collection from the Monash Lupus Clinic at the Monash Medical Centre, the only lupus-dedicated clinic in Australia.
Provided by Monash University
- First lupus breakthrough in 50 years Apr 28, 2011 | not rated yet | 0
- Vitamin D insufficiency prevalent among psoriatic arthritis suffers Jul 11, 2011 | not rated yet | 0
- Oral steroids linked to severe vitamin D deficiency in nationwide study Sep 29, 2011 | not rated yet | 0
- Vitamin D found to influence over 200 genes, highlighting links to disease Aug 23, 2010 | not rated yet | 0
- Pregnant women at risk of Vitamin D deficiency Apr 05, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
(HealthDay)—Few randomized clinical trials have been done to assess clinical prediction rules for patients with lower back pain, and the trials that have been done are of low quality and do not provide ...
Diseases, Conditions, Syndromes 18 hours ago | not rated yet | 0 |
A new, highly sensitive blood test that quickly detects even the lowest levels of malaria parasites in the body could make a dramatic difference in efforts to tackle the disease in the UK and across the world, according to ...
Diseases, Conditions, Syndromes 23 hours ago | not rated yet | 0
(AP)—The World Health Organization says a yellow fever booster vaccination given 10 years after the initial shot isn't necessary.
Diseases, Conditions, Syndromes 23 hours ago | not rated yet | 0
(AP)—Twenty-three youths have died in the past nine days at initiation ceremonies that include circumcisions and survival tests, South African police said Friday.
Diseases, Conditions, Syndromes May 17, 2013 | 5 / 5 (1) | 3
The United States government public health agency, the CDC, pledges "To base all public health decisions on the highest quality scientific data, openly and objectively derived." But Peter Doshi, a postdoctoral fellow at Johns ...
Diseases, Conditions, Syndromes May 16, 2013 | not rated yet | 0
Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.
7 hours ago | 5 / 5 (1) | 0
For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests
Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...
8 hours ago | not rated yet | 0 |
(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...
20 hours ago | 3.7 / 5 (3) | 0 |
The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...
19 hours ago | not rated yet | 0 |
In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...
17 hours ago | 3.7 / 5 (3) | 0 |
Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic. Multiple factors can influence both the type and degree of neurocognitive abnormalities ...
17 hours ago | not rated yet | 0 |