Researchers say urine dipstick test is accurate predictor of renal failure in sepsis patients

May 14, 2012

Henry Ford Hospital researchers have found that the presence of excess protein in a common urine test is an effective prognostic marker of acute renal failure in patients with severe sepsis.

Researchers analyzed data from 328 sepsis patients with no previous history of protein in the urine and found the urine dipstick test predicted the presence of renal failure in 55 percent of these patients.

A urine dipstick test is routinely done as part of a urinalysis to help diagnose urinary tract infections, kidney disease, diabetes and sepsis, the deadly . After a urine sample is taken, a specially treated chemical strip is placed into the sample. Patches on the dipstick will change color to indicate the presence of such things as , protein, or glucose.

Many studies have shown the dipstick test to be a rapid detector for identifying urinary tract infections. Henry Ford researchers evaluated for the first time the dipstick test for its accuracy of identifying renal failure in sepsis patients.

Results of the study were presented Thursday at the National Kidney Foundation's annual meeting in Washington, D.C.

"This is a useful test that is widely available and inexpensive," says Javier Neyra, M.D., a third-year resident at Henry Ford and the study's lead author.

Dr. Neyra says the dipstick test , or proteinria, resulted in fewer false positives and a greater threshold for detecting more severe renal failure compared to other biomarkers. Ultimately, he says, the test may provide timely and early diagnosis of renal failure before substantial damage has already been done.

Explore further: Women at higher risk than men of kidney damage after heart imaging test

Related Stories

Recommended for you

Monkeys in Asia harbor virus from humans, other species

November 19, 2015

When it comes to spreading viruses, bats are thought to be among the worst. Now a new study of nearly 900 nonhuman primates in Bangladesh and Cambodia shows that macaques harbor more diverse astroviruses, which can cause ...

One-step test for hepatitis C virus infection developed

November 14, 2015

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.