Researchers say urine dipstick test is accurate predictor of renal failure in sepsis patients

Henry Ford Hospital researchers have found that the presence of excess protein in a common urine test is an effective prognostic marker of acute renal failure in patients with severe sepsis.

Researchers analyzed data from 328 sepsis patients with no previous history of protein in the urine and found the urine dipstick test predicted the presence of renal failure in 55 percent of these patients.

A urine dipstick test is routinely done as part of a urinalysis to help diagnose urinary tract infections, kidney disease, diabetes and sepsis, the deadly . After a urine sample is taken, a specially treated chemical strip is placed into the sample. Patches on the dipstick will change color to indicate the presence of such things as , protein, or glucose.

Many studies have shown the dipstick test to be a rapid detector for identifying urinary tract infections. Henry Ford researchers evaluated for the first time the dipstick test for its accuracy of identifying renal failure in sepsis patients.

Results of the study were presented Thursday at the National Kidney Foundation's annual meeting in Washington, D.C.

"This is a useful test that is widely available and inexpensive," says Javier Neyra, M.D., a third-year resident at Henry Ford and the study's lead author.

Dr. Neyra says the dipstick test , or proteinria, resulted in fewer false positives and a greater threshold for detecting more severe renal failure compared to other biomarkers. Ultimately, he says, the test may provide timely and early diagnosis of renal failure before substantial damage has already been done.

add to favorites email to friend print save as pdf

Related Stories

IgM in urine acts as prognostic indicator in diabetes

Aug 04, 2009

A marker of the likely course of diabetic nephropathy (DN) has been found. An 18-year study, published in the open access journal BMC Medicine, has shown that Immunoglobulin M (IgM) is a reliable predictor of cardiovascular compli ...

New urine test could diagnose acute kidney injury

Nov 11, 2010

The presence of certain markers in the urine might be a red flag for acute kidney injury (AKI), according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results sugge ...

Recommended for you

Big strides made in fighting TB, says WHO

57 minutes ago

The known tally of people with tuberculosis rose last year but overall "major progress" is being made in rolling back the disease, the World Health Organization (WHO) said Wednesday.

In US, Ebola fears rise but most confident in response

6 hours ago

After two health care workers in Texas were infected with Ebola while caring for a Liberian patient, a poll Tuesday showed a rattled US public that nevertheless stayed confident in the government's response.

'Humbled' NBC cameraman recovers from Ebola

6 hours ago

A US photojournalist said Tuesday he was grateful to be alive after the hospital treating him declared him now free of Ebola, in a minor victory over the virus that has killed more than 4,500 people.

User comments