Sleep apnea severity linked to glycated hemoglobin levels

Sleep apnea severity linked to glycated hemoglobin levels
For adults without diabetes, obstructive sleep apnea severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin levels, according to a study published online June 11 in Diabetes Care.

(HealthDay) -- For adults without diabetes, obstructive sleep apnea (OSA) severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels, according to a study published online June 11 in Diabetes Care.

Pascaline Priou, M.D., of LUNAM University in Angers, France, and colleagues conducted a large cross-sectional study involving 1,599 patients with OSA. HbA1c levels were measured, and patients with diabetes, use of , or HbA1c levels ≥6.5 percent were excluded.

The researchers found that increased with increasing OSA severity, as measured by the apnea-hypopnea index (AHI), with the percent of patients with HbA1c increasing from 10.8 to 34.2 percent for those with AHI values <5 to ≥50, respectively. After adjusting for potential confounding factors, the odds ratios of a patient having an HbA1c level >6.0 percent increased from 1.0 (reference) for AHI <5; to 1.40 for AHI of ≥5 to <15; to 1.8 for AHI of ≥15 to <30; to 2.02 for AHI of ≥30 to <50; to 2.96 for AHI of ≥50. Additionally, an independent association was found between increasing hypoxemia during sleep and the odds of an elevated HbA1c level.

"Among adults without known diabetes, increasing OSA severity is independently associated with impaired , as assessed by higher HbA1c values, which may expose them to higher risks of diabetes and cardiovascular disease," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Obstructive sleep apnea may worsen diabetes

date Jan 14, 2010

Obstructive Sleep Apnea (OSA) adversely affects glucose control in patients with type 2 diabetes, according to a study conducted by researchers at the University of Chicago.

Study assesses glucose monitoring trends in tweens

date Apr 12, 2012

(HealthDay) -- During the transition to adolescence, children with type 1 diabetes monitor their blood glucose less frequently, resulting in significant increases in HbA1c levels, according to research published ...

Recommended for you

Sleep apnea linked to depression in men

date May 18, 2015

Severe obstructive sleep apnea (OSA) and excessive daytime sleepiness are associated with an increased risk of depression in men, according to a new community-based study of Australian men, which was presented at the 2015 ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.