Risk of calcium oxalate stones not affected by oxalate intake

Risk of calcium oxalate stones not affected by oxalate intake
Eating large amounts of oxalate does not significantly affect the risk of developing calcium oxalate stones if the recommended amount of dietary calcium is also eaten, according to a study published in the June issue of Urology.

(HealthDay) -- Eating large amounts of oxalate does not significantly affect the risk of developing calcium oxalate stones if the recommended amount of dietary calcium is also eaten, according to a study published in the June issue of Urology.

Jessica N. Lange, M.D., of the Wake Forest University School of Medicine in Winston-Salem, N.C., and colleagues conducted a study involving 10 adults who were placed on a balanced calcium/oxalate ratio diet (calcium, 1,000 mg; oxalate, 750 mg) for one week, observed a one-week washout period, and finally, were allowed to eat an imbalanced calcium/oxalate ratio diet for one week. The objective of the study was to evaluate whether dietary calcium and oxalate consumption at mealtime affects the of oxalate from the or the of oxalate in the urine.

The researchers found that, in both balanced an imbalanced phases, the total daily calcium excretion, oxalate excretion, and Tiselius index were similar. Urinary calcium excretion was significantly lower in the balanced versus imbalanced diets in the 1 to 6 p.m. and 6 to 11 p.m. time periods, and was significantly higher in the 11 p.m. to 8 a.m. collection. Oxalate excretion was significantly higher on the versus the imbalanced diet during the 1 to 6 p.m. time period. No differences in the Tiselius index were observed.

"In conclusion, these results demonstrate that the sequence of consuming a moderate to large amount of food-derived oxalate does not significantly affect calcium oxalate stone risk if the recommended daily quantity of is eaten," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Of mice and men... and kidney stones

Mar 01, 2008

Kidney stones are very common – and painful – in men. About 3 in 20 men (1 in 20 women) in developed countries develop them at some stage. Mice, however, rarely suffer though the precise reasons are unknown. Jeffrey ...

Study finds bacteria may reduce risk for kidney stones

Mar 05, 2008

Researchers from Boston University’s Slone Epidemiology Center have found that the bacteria Oxalobacter formigenes (O. formigenes), a naturally occurring bacterium that has no known side effects, is associated with a 70 ...

Bacteria munch up alumina impurities

Jul 19, 2010

Previously unknown species of naturally-occurring bacteria have the potential to save the alumina and aluminium industries millions of dollars while helping to reduce their impact on the environment, microbiologist ...

Recommended for you

Ebola isolation at US base 'pretty much vacation'

2 hours ago

With plenty of flat screen TVs, game nights and even an outdoor fire pit, life in isolation for members of the U.S. military who have returned from the Ebola mission in West Africa can look a lot like summer camp.

Chinese-built Ebola center dedicated in Liberia

6 hours ago

China, one of the first countries to send aid to battle Ebola in West Africa, ramped up the assistance significantly Tuesday by opening a 100-bed treatment center in Liberia as rows of uniformed Chinese army ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.