Diabetes linked to increased cause-specific mortality

June 21, 2012
Diabetes linked to increased cause-Specific mortality
Diabetes is linked with a significantly increased risk of death from many diseases, including specific cancers, in both men and women, according to a study published online June 14 in Diabetes Care.

(HealthDay) -- Diabetes is linked with a significantly increased risk of death from many diseases, including specific cancers, in both men and women, according to a study published online June 14 in Diabetes Care.

Peter T. Campbell, Ph.D., of the National Home Office in Atlanta, and colleagues conducted a involving 1,053,831 adults in the United States enrolled in the Cancer Prevention Study-II who were followed for up to 26 years. Participants completed a self-administered questionnaire at baseline, and the association of diabetes with cause-specific mortality was assessed.

The researchers found that women and men with diabetes had an increased risk of all-cause mortality, after controlling for age, , and other variables (relative risk [RR], 1.90 and 1.73, respectively). Diabetes correlated with increased risk of death from cancers of the liver (RR, 1.40), pancreas (RR, 1.31), endometrium (RR, 1.33), colon (RR, 1.18), and breast (RR, 1.16) for women. For men there was an increased risk of death from cancers of the breast (RR, 4.20), liver (2.26), oral cavity and pharynx (RR, 1.44), pancreas (RR, 1.40), bladder (RR, 1.22), and colon (RR, 1.15). There was an inverse association with prostate cancer (RR, 0.88). Diabetes correlated with increased mortality linked to the circulatory system, respiratory system, digestive system, genitourinary system, and accidental deaths/external causes.

"In conclusion, the broad range of deaths associated with diabetes in this study reflect the extensive nature of the disease," the authors write. "These findings support the need for coordinated, multidisciplinary care of men and women with diabetes, including age-appropriate and early detection."

Explore further: Smoking is an independent risk factor for psoriasis

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Smoking is an independent risk factor for psoriasis

March 7, 2012

(HealthDay) -- Smoking is an independent risk factor for psoriasis, with particularly strong associations for heavy smokers and those who have smoked for many years, according to research published in the March 1 issue of ...

Cancer risk up in bilateral retinoblastoma survivors

February 23, 2012

(HealthDay) -- For survivors of bilateral retinoblastoma (Rb), family history is associated with an increased risk of second cancers (SCs), especially melanoma, according to a study published online Feb. 21 in the Journal ...

Declines in melanoma deaths limited to the most educated

January 16, 2012

A new study from the American Cancer Society finds recent declines in melanoma mortality rates in non-Hispanic Whites in the U.S. mainly reflect declines in those with the highest level of education, and reveals a widening ...

Recommended for you

New theory on how insulin resistance, metabolic disease begin

September 26, 2016

Does eating too much sugar cause type 2 diabetes? The answer may not be simple, but a study published Sept. 26 in the Journal of Clinical Investigation adds to growing research linking excessive sugar consumption—specifically ...

Unique molecular atlas of pancreas produced

September 23, 2016

Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between ...

Can long naps cause diabetes?

September 14, 2016

A study presented at a scientific congress Thursday reported a link between long naps and a higher risk of diabetes, though it couldn't say if daytime sleeping was a symptom or a cause.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.