Imaging can detect response to dry mouth toothpaste

Imaging can detect response to dry mouth toothpaste
In vivo optical coherence tomography imaging can detect response to dry mouth toothpaste in patients with xerostomia, according to a pilot study published online June 13 in Lasers in Surgery and Medicine.

(HealthDay) -- In vivo optical coherence tomography (OCT) imaging can detect response to dry mouth toothpaste in patients with xerostomia, according to a pilot study published online June 13 in Lasers in Surgery and Medicine.

Steven Duong, from the University of California in Irvine, and colleagues randomized 10 patients with xerostomia to a dry mouth toothpaste versus placebo. Participants used the first product for 15 days, followed by a seven-day washout period, and then they used the second product for 15 days. The sequence of product use was randomized. Data were acquired at five-day intervals, before and after the washout. Participants were examined and assessed with OCT imaging.

The researchers found that there was no response to the product observed in either visual examination or the tongue blade adhesion test. Imaging identified that epithelial thickness increased significantly after use of the dry mouth toothpaste, but it did not change significantly after the use of fluoride toothpaste. Progressive characteristic changes from baseline seen on optical backscattering occurred with use of the dry mouth product.

"In this using in vivo OCT imaging, it was possible to detect and measure oral epithelial response to the dry mouth product versus placebo in patients with xerostomia," the authors write.

Colgate Palmolive Company contributed to the funding of the study.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Counterfeit toothpaste is discovered

Jun 14, 2007

The U.S. Food and Drug Administration said a counterfeit toothpaste falsely packaged as "Colgate" has been found in four states.

More Chinese-made toothpaste is recalled

Jul 17, 2007

The U.S. Food and Drug Administration Monday announced the nationwide recall of DentFresh Fluoride Mint Toothpaste because of possible contamination.

Study finds ways to help end dry mouth in cancer patients

May 04, 2011

(Edmonton) For patients suffering from cancer in the mouth or throat, a recent study shows that a treatment called submandibular gland transfer will assist in preventing a radiation-induced condition called xerostomia.

Dry mouth linked to prescription and over the counter drugs

Jul 09, 2009

Approximately ninety-one percent of dentists say patients complaining about dry mouth are taking multiple medications, according to a nationwide member survey conducted by the Academy of General Dentistry (AGD). Dry mouth, ...

Recommended for you

Mystery of the reverse-wired eyeball solved

Feb 27, 2015

From a practical standpoint, the wiring of the human eye - a product of our evolutionary baggage - doesn't make a lot of sense. In vertebrates, photoreceptors are located behind the neurons in the back of the eye - resulting ...

Neurons controlling appetite made from skin cells

Feb 27, 2015

Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight ...

Quality control for adult stem cell treatment

Feb 27, 2015

A team of European researchers has devised a strategy to ensure that adult epidermal stem cells are safe before they are used as treatments for patients. The approach involves a clonal strategy where stem cells are collected ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.