IU gastroenterologist develops practice guidelines for most prevalent liver disease

An Indiana University School of Medicine gastroenterologist led a team of distinguished physicians who developed the first guidelines for diagnosis and management of non-alcoholic fatty liver disease. The guidelines were published simultaneously in the June issues of the journals Hepatology, Gastroenterology and the American Journal of Gastroenterology.

Naga P. Chalasani, M.B.B.S., professor of medicine and director of the Division of Gastroenterology and Hepatology at the IU School of Medicine and a member of IU Health Physicians, said non-alcoholic is expected to become the No. 1 reason for in the next 10 to 15 years.

Dr. Chalasani, who is the lead author of the journal article, said this is the first time practice guidelines have been developed for the condition by the three major medical societies: the American Association for the Study of Liver Diseases, the American College of Gastroenterology and the American Gastroenterological Association.

"Although the condition has been recognized for 100 years, because of the increasing frequency of obesity, diabetes and metabolic syndrome, the prevalence and incidence of non-alcoholic fatty liver disease is rapidly becoming the most common cause of cirrhosis in the United States," Dr. Chalasani said. The disease also can cause and , he said.

Practice guidelines offer evidence-based information to help health care providers diagnose and manage patients with a specific disease. The guidelines can include treatment options, dosage recommendations, information on risk versus benefits, and cost-effectiveness of treatments, and they help standardize medical care.

Guidelines typically are written at a national level by medical associations or government bodies.

add to favorites email to friend print save as pdf

Related Stories

Fatty liver disease can lead to heart attack

Apr 19, 2011

Because of the prevalence of obesity in our country, many Americans are expected to develop a serious condition called non-alcoholic fatty liver disease (NAFLD), which can lead to cirrhosis, fibrosis, and in some cases liver ...

Recommended for you

Ebola: Keeping patients alive as body fights back

5 hours ago

People who shared an apartment with the first U.S. Ebola patient are emerging from quarantine healthy. And while Thomas Eric Duncan died and two U.S. nurses were infected caring for him, there are successes, ...

Study suggests altering gut bacteria might mitigate lupus

5 hours ago

Lactobacillus species, commonly seen in yogurt cultures, correlate, in the guts of mouse models, with mitigation of lupus symptoms, while Lachnospiraceae, a type of Clostridia, correlate with worsening, according to researc ...

User comments