Poorest bowel cancer patients more likely to die within month of surgery
(Medical Xpress) -- Bowel cancer patients living in the most deprived areas are 24 per cent more likely to die within five years of treatment than their more affluent neighbours and this difference appears to be a result of excess deaths within the first 30 days following surgery to treat the disease.
These are the findings of new data presented at the annual National Cancer Intelligence Network (NCIN) conference in Birmingham.1
Researchers at the West of Scotland Cancer Surveillance Unit working in collaboration with the West of Scotland Colorectal Cancer Managed Clinical Network looked at nearly 4,300 patients who had surgery for bowel cancer. The study compared patients of the same age at diagnosis and sex in the various socioeconomic groups.2
The results showed that survival for five-years after surgery for bowel cancer was lower among patients from the most deprived areas - 59.5 per cent of patients analysed compared with 69.7 per cent among the most affluent patients.
The researchers said that this was partly because more patients from deprived areas were diagnosed with bowel cancer through emergency presentations, with the disease at a later stage.3
Patients from more deprived areas were also more likely to have other illnesses and surgery was less likely to cure the disease compared to those from more affluent areas. These factors have lead to bowel cancer patients from deprived areas being more likely to die within 30 days of having surgery.
Raymond Oliphant, lead researcher and a clinical research fellow based at the University of Glasgows West of Scotland Cancer Surveillance Unit, said: This research further highlights that survival following treatment for bowel cancer is better in people from the most affluent areas and worst among the most deprived.
This study builds on previous research in this area by giving more detail on both short and longer term survival differences between patients from different economic backgrounds and will help those working on ways to improve outcomes for bowel cancer patients.
When researchers excluded patients who died within the first 30-days of surgery from their analysis, they found no difference in survival between socioeconomic groups.
This suggests that the biggest impact on survival between deprived and affluent patients happens in the very first few weeks after surgery.
Chris Carrigan, head of the NCIN, said: This study once again stresses the urgent need to improve the health of people living in deprived areas and to make sure all cancer patients have an equal chance of surviving their cancer.
Deprivation is one of the biggest causes of cancer inequality in this country. We know that people from more deprived areas are more likely to smoke or be very overweight. They are also less likely to be aware of signs and symptoms of cancer, probably leading to later diagnosis, which may further increase their chances of dying from their disease.
We need to take a close look at factors like late diagnosis, uptake of screening and variations in treatment for people from different social and economic backgrounds if we are to reduce inequality in cancer survival.
But in the meantime everyone can do their bit by giving up smoking, which increases the risk of other diseases which affect the outcome of surgery, eating sensibly and seeing a GP as soon as possible if they notice anything unusual about their body.
More information: 1. Oliphant, R et al,. The influence of socioeconomic circumstances on survival after surgery for colorectal cancer (2012)
2. Deprivation is calculated using the area-based Scottish Index of Multiple Deprivation this calculates deprivation by generating a score for small population areas (containing 750 people based on postcode) derived from detailed information on seven key areas: 1) income and benefits 2) employment in working age population 3) health and healthcare utilisation 4) educational attainment, skills and training 5) access to services 6) recorded crime rates and 7) housing quality and overcrowding. Overall area scores are then ranked from the least to most deprived and are presented in five equal groups.
3. Among the most deprived group of patients, 23.5 per cent were diagnosed with bowel cancer through emergency presentations compared with 19.5 per cent in the most affluent group.
There were fewer stage A (early stage) tumours in the most deprived group (12.5 per cent) compared to the most affluent group (17.9 per cent).
73.3 per cent of the most deprived group were treated by major surgery compared with 82.6 per cent in the most affluent group of patients.
9.6 per cent of the most deprived patients died within 30 days of having surgery to treat bowel cancer compared with 4.2 per cent in the most affluent group.
The study looked at patients diagnosed with bowel cancer in the West of Scotland from January 2001 to December 2004 identified from the Scottish Cancer Registry linked to clinical audit data from the West of Scotland Colorectal Cancer Managed Clinical Network .
Provided by Cancer Research UK
- Bowel cancer rates fall among rich men only Jun 01, 2011 | not rated yet | 0
- Poor men more likely to die from bowel cancer Nov 07, 2011 | not rated yet | 0
- Nearly 10 per cent of bowel cancer patients die within a month of diagnosis Mar 27, 2012 | not rated yet | 0
- Men from deprived areas less likely to be treated for prostate cancer Apr 22, 2010 | not rated yet | 0
- Latest cancer research unveiled Jun 20, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
Marie Curie's leukemia
May 13, 2013 Does anyone know what might be the cause of Marie Curie's cancer
- More from Physics Forums - Medical Sciences
More news stories
The use of a smartphone application significantly improves patients' preparation for a colonoscopy, according to new research presented today at Digestive Disease Week (DDW). The preparation process, which begins days in ...
Cancer 12 hours ago | not rated yet | 0
Research presented at Digestive Disease Week (DDW) explores new methods for managing digestive health through diet and lifestyle.
Cancer 12 hours ago | not rated yet | 1
A ground-breaking advance in colonoscopy technology signals the future of colorectal care, according to research presented today at Digestive Disease Week(DDW). Additional research focuses on optimizing the minimal withdrawal ...
Cancer May 18, 2013 | 5 / 5 (2) | 0
(HealthDay)—Concurrent use of two immune checkpoint antibodies—ipilimumab and nivolumab—may be effective for the treatment of advanced melanoma, according to a proof-of-principal study presented in ...
Cancer May 17, 2013 | not rated yet | 0
(HealthDay)—The risks of metastasis and death associated with cutaneous squamous cell carcinoma (CSCC) are low, but significant, and risk factors for poor outcome include tumor diameter, invasion beyond ...
Cancer May 17, 2013 | not rated yet | 0 |
In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual ...
1 hour ago | not rated yet | 0 |
Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, ...
1 hour ago | not rated yet | 0 |
Researchers at the University of Wisconsin have identified a potential new risk factor for obstructive sleep apnea: asthma. Using data from the National Institutes of Health (Heart, Lung, and Blood Institute)-funded Wisconsin ...
4 minutes ago | not rated yet | 0 |
A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.
14 minutes ago | not rated yet | 0 |
Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study from researchers at Columbia University shows purified components of the ...
4 minutes ago | not rated yet | 0
The hunt for an HIV vaccine has gobbled up $8 billion in the past decade, and the failure of the most recent efficacy trial has delivered yet another setback to 26 years of efforts.
4 hours ago | not rated yet | 0