Skin testing not sufficient to ID contrast media sensitivity
More than 50 percent of patients with nonimmediate reactions to iodinated contrast media are identified with the drug provocation test and not with skin testing, according to a study published online May 15 in Allergy.
(HealthDay) -- More than 50 percent of patients with nonimmediate reactions to iodinated contrast media (CM) are identified with the drug provocation test (DPT) and not with skin testing, according to a study published online May 15 in Allergy.
Maria J. Torres, M.D., Ph.D., of Carlos Haya Hospital in Malaga, Spain, and associates investigated the role of skin testing and the DPT in the diagnosis of nonimmediate reactions to CM in 161 patients. Skin intradermal and patch testing were performed with different CM. In cases with a negative skin test, a single-blind placebo-controlled DPT was performed.
The researchers found that 21.1 percent of the subjects were skin-test positive to the various CM. In 34.6 percent of skin-test negative cases the DPT was positive. Of the 78 cases with confirmed hypersensitivity, 56.4 percent were identified by DPT and 43.6 percent were identified by skin testing.
"We conclude that skin-test sensitivity is not sufficient and that, in more than 50 percent of cases, a DPT is also needed to establish the diagnosis," the authors write.
More information: Abstract
Full Text (subscription or payment may be required)
Journal reference:
Allergy
Copyright © 2012 HealthDay. All rights reserved.
-
The Medical Minute: Food allergies -- testing and diagnosis
May 09, 2012 |
not rated yet |
0
-
Skin tests catch metal sensitivity before joint replacement
Feb 24, 2012 |
not rated yet |
0
-
New national study links asthma to allergies
Sep 27, 2007 |
not rated yet |
0
-
Objective evidence of skin infestation lacking in patients with diagnosis of delusional infestation
May 16, 2011 |
not rated yet |
0
-
Kids' penicillin allergy may not signal other drug reactions
Mar 08, 2012 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Noise dependence
43 minutes ago
-
siphon and bernouli theorum
2 hours ago
-
Hot gas expansion rate into outer space
2 hours ago
-
Magnetic field lines through copper
7 hours ago
-
Lagrangian of object with air resistance
9 hours ago
-
Does electromagnetic waves are generated by dc current?
9 hours ago
- More from Physics Forums - Classical Physics
More news stories
Pollen count apps for smartphones are nothing to sneeze at
Kate O'Reilly's spring allergy survival kit includes the usual stuff - nasal sprays, allergy pills and a box of tissues. This season, she's added a new weapon to her line of defense: an app on her smartphone.
Immunology
22 hours ago |
not rated yet |
0
Going live: Immune cell activation in multiple sclerosis
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
Immunology
May 24, 2013 |
5 / 5 (5) |
0
|
Vaccine blackjack: IL-21 critical to fight against viral infections
(Medical Xpress)—Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections.
Immunology
May 23, 2013 |
5 / 5 (2) |
0
|
Fast-acting mothers' milk for healthier babies
Human breastmilk responds quickly to protect the child when there is an infection in mothers or babies, according to new international research led by The University of Western Australia.
Immunology
May 23, 2013 |
5 / 5 (1) |
0
New immune system discovered
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
Immunology
May 20, 2013 |
4.8 / 5 (30) |
9
|
First drug to improve heart failure mortality in over a decade
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
Heart failure accelerates male 'menopause'
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
Death highest in heart failure patients admitted in January, on Friday, and overnight
Mortality and length of stay are highest in heart failure patients admitted in January, on Friday, and overnight, according to research presented today at the Heart Failure Congress 2013. The analysis of nearly 1 million ...
Feds fight morning-after pill age ruling in NY
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
Researchers identify first drug targets in childhood genetic tumor disorder
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
Driving and hands-free talking lead to spike in errors, study shows
Talking on a hands-free device while behind the wheel can lead to a sharp increase in errors that could imperil other drivers on the road, according to new research from the University of Alberta.
