Researchers develop new method for identifying lung nodules

July 16, 2012

Pulmonary nodules are common, but few studies of lung nodule identification and clinical evaluation have been performed in community settings. Researchers from Kaiser Permanente Southern California identified 7,112 patients who had one or more nodules by using existing information within the electronic medical record.

Their study presented in the August 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) , showed how researchers developed and implemented a new method for identifying in community-based settings.

The researchers used a combination of ICD-9 codes, CPT codes and an algorithm for (NLP) to classify the nodules. This automated method had a 96 percent sensitivity and 86 percent specificity compared to clinician review.

The authors suggest that the automated process, "could be used to study the incidence and prevalence of lung nodules in large popula¬tions, with the caveat that approximately 13 percent of cases identi¬fied by the automated method would not meet our definition of one or more nodules (e.g., be false-positives)."

Since this study favored sensitivity over specificity, the authors advise that the method "could be used as a sensitive first step to be followed by more specific review of radiology transcripts or actual imaging studies."

As screening programs for lung cancer have proven to be beneficial in specific high-risk populations, this study also provides useful information for the study of screen-detected nodules.

Explore further: PET outperforms CT in characterization of lung nodules

Related Stories

PET outperforms CT in characterization of lung nodules

February 6, 2008

Researchers involved in a large, multi-institutional study comparing the accuracy of positron emission tomography (PET) and computed tomography (CT) in the characterization of lung nodules found that PET was far more reliable ...

Microcoils help locate small lung nodules

February 2, 2009

A new technique combining computed tomography (CT) with fiber-coated surgical microcoils allows physicians to successfully locate and remove small lung nodules without the need for a more invasive procedure, according to ...

Recommended for you

Oxygen can impair cancer immunotherapy in mice

August 25, 2016

Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers. This mechanism involves oxygen inhibition of the anticancer ...

Stem cell propagation fuels cancer risk in different organs

August 25, 2016

The idea that stem cells - special cells that divide to repair and generate tissues - might be the major determinant of cancer risk has provoked great debate in the scientific community. Some researchers maintain that environmental ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.