Supplement mixture improves memory in mild Alzheimer's

Supplement mixture improves memory in mild alzheimer's
A supplement mixture (Souvenaid) containing dietary precursors and specific nutrients can improve memory in drug-naive patients with mild Alzheimer's disease, according to a study published in the July issue of the Journal of Alzheimer's Disease.

(HealthDay) -- A supplement mixture (Souvenaid) containing dietary precursors and specific nutrients can improve memory in drug-naive patients with mild Alzheimer's disease (AD), according to a study published in the July issue of the Journal of Alzheimer's Disease.

Philip Scheltens, M.D., from the VU University Medical Center in Amsterdam, and colleagues conducted a 24-week, randomized, controlled trial in which drug-naive patients with mild AD were randomized in a 1:1 ratio to receive Souvenaid or an iso-caloric control product once daily. was assessed using the domain z-score of the Neuropsychological Test Battery (NTB).

The researchers found that, over the intervention period, the NTB memory domain z-score was significantly increased in patients taking Souvenaid versus the control group (P = 0.023), with a trend toward improvement in the NTB total composite z- score (P = 0.053). in the delta band, as measured by an electroencephalography, was significantly different between the study groups in favor of the active group. There was very high adherence to the intervention (96.6 percent for the control and 97.1 percent for the active group). Both products were well tolerated and there was no between-group difference in the occurrence of .

"In conclusion, this study confirms that Souvenaid is well tolerated and improves ," the authors write. "Our results warrant further investigation of the clinical potential of Souvenaid in preclinical or clinical conditions characterized by synaptic loss, in particular AD."

Several authors disclosed to Danone Research BV and Nutricia Advanced Medical Nutrition, which sponsored the study and manufacture Souvenaid.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Nutritional intervention helps in mild Alzheimer's disease

Nov 05, 2011

A second clinical trial of the medical food Souvenaid confirmed that daily intake of the nutritional intervention improves memory in people with mild Alzheimer's disease (AD). Results of the trial - called Souvenir II - were ...

Recommended for you

World first effort to prevent dementia in high-risk people

Oct 15, 2014

Dementia will soon engulf more than 100 million people across the globe, but an international research group is leading a world-first effort to prevent dementia in people who are at high risk of this insidious disease.

Aluminium and its likely contribution to Alzheimer's disease

Oct 13, 2014

A world authority on the link between human exposure to aluminium in everyday life and its likely contribution to Alzheimer's disease, Professor Christopher Exley of Keele University, UK, says in a new report that it may ...

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

Shakescene21
not rated yet Jul 12, 2012
What are the ingredients of this magic potion? This article leaves out the most important relevant information, and is little more than a promo for a planned commercial product.