After bariatric op, controlled diet can aid CaOx supersaturation

After bariatric op, controlled diet can aid CaOx supersaturation
After bariatric surgery, following a diet that is normal in calcium, low in oxalate, and moderate in protein, can improve urinary calcium oxalate supersaturation, but not urinary oxalate excretion, in patients with a history of kidney stones, according to a study published in the August issue of Urology.

(HealthDay) -- After bariatric surgery, following a diet that is normal in calcium, low in oxalate, and moderate in protein, can improve urinary calcium oxalate (CaOx) supersaturation, but not urinary oxalate excretion, in patients with a history of kidney stones, according to a study published in the August issue of Urology.

Using data from nine patients with a history of CaOx and mild hyperoxaluria who underwent bariatric surgery, Ran Pang, from the Mayo Clinic in Rochester, Minn., and colleagues investigated the effect of a controlled metabolic diet on reducing urinary CaOx supersaturation. Baseline 24-hour were collected while participants consumed a free choice diet. Before two final 24-hour urine collections, participants were then instructed to consume a controlled diet low in oxalate (70 to 80 mg/day), normal in calcium (1,000 mg/day), and moderate in protein.

The researchers found that urinary CaOx supersaturation decreased significantly, from 1.97 ± 0.49 delta Gibbs (DG) with the free choice diet to 1.13 ± 0.75 DG with the controlled diet. This decrease occurred without a significant alteration in urinary oxalate (0.69 ± 0.29 mmol/day with the free choice diet versus 0.66 ± 0.38 mmol/day with the controlled diet). The change in CaOx supersaturation was partially due to nonsignificant increases in urinary volume, citrate, and pH.

"The results of the present study suggest that a diet, normal in calcium and moderate in protein, can improve urinary CaOx supersaturation in patients after bariatric surgery," the authors write. "However, such a balanced low-oxalate diet did not normalize urinary oxalate excretion by itself."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Study finds bacteria may reduce risk for kidney stones

Mar 05, 2008

Researchers from Boston University’s Slone Epidemiology Center have found that the bacteria Oxalobacter formigenes (O. formigenes), a naturally occurring bacterium that has no known side effects, is associated with a 70 ...

Gastric bypass surgery increases risk of kidney stones

Mar 10, 2010

March 11, 2010 - Patients who undergo gastric bypass surgery experience changes in their urine composition that increase their risk of developing kidney stones, research from UT Southwestern Medical Center investigators suggests.

Of mice and men... and kidney stones

Mar 01, 2008

Kidney stones are very common – and painful – in men. About 3 in 20 men (1 in 20 women) in developed countries develop them at some stage. Mice, however, rarely suffer though the precise reasons are unknown. Jeffrey ...

Recommended for you

Ebola aid dogged by coordination lags in Guinea

21 hours ago

Eight months into West Africa's Ebola outbreak, aid efforts in Guinea still suffer from poor coordination, hampering deployments of international support to help quell a virus that has killed more than 1,200 ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.