MR enterography is option for pediatric patients with Crohn disease

Parents with children nine years old and older who have Crohn disease should ask their children's doctor about MR enterography as a replacement for small bowel x-rays or CT enterography, a new study indicates.

Children with must often undergo repeated examinations, which, with x-rays and CT, could lead to significant , said William A. Faubion, Jr., MD, one of the authors of the study.

"MR enterography does not require any radiation, however the patient does have to drink an oral contrast agent, must hold their breath at times and must limit their motion during the examination, all which can be difficult for ," said Dr. Faubion.

The study—the largest North American study of its kind-- analyzed 70 pediatric patients who underwent MR enterography to review the quality of MR enterography images and to determine if pediatric patients could tolerate the examination. The study, conducted at Mayo Clinic College of Medicine in Rochester, MN, found that "MR enterography performs as well in children as it does in adults. MR enterography could accurately identify inflammation 80% of the time in the terminal ileum, 79% of the time in the right colon and 90% of the time in the left colon," said Dr. Faubion. While a similar study using CT in children has not been performed, in adults MR and CT enterography have been found to be equivalent methods of imaging, said Dr. Faubion.

"In addition, we found that MR enterography could be successfully completed in the majority of children nine years old and older, without having to sedate them," Dr. Faubion said. The number of patients who suffered side effects was low; two patients experienced nausea and one patient fainted, however, no ongoing care was required, he said. One patient refused to drink the contrast material. Tolerance to the procedure was related to the amount of contrast the patient had to drink; the study found that younger could drink a smaller amount of contrast material without negatively affecting the MR enterography image quality, Dr. Faubion said.

The study appears in the September issue of the American Journal of Roentgenology.

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

S.Korea detects second foot-and-mouth case

1 hour ago

South Korea on Monday reported its second case of foot-and-mouth disease in less than a week, triggering fearful memories of a devastating 2011 outbreak that forced the culling of millions of livestock.

Ebola kills Liberian doctor, 2 Americans infected

2 hours ago

(AP)—One of Liberia's most high-profile doctors has died of Ebola, officials said Sunday, and an American physician was being treated for the deadly virus, highlighting the risks facing health workers trying ...

Hepatitis C virus genotype 1 is most prevalent worldwide

2 hours ago

In one of the largest prevalence studies to date, researchers from the U.K. provide national, regional, and global genotype prevalence estimates for the hepatitis C virus (HCV). Findings published in Hepatology, a journa ...

1 in 3000 blood donors in England infected with hepatitis E

2 hours ago

The first systematic analysis of hepatitis E virus (HEV) transmission by blood components indicates that about 1 in 3000 donors in England have HEV in their plasma. The findings, published in The Lancet, suggest that around ...

Biologic treatments for RA carry similar infection risk

2 hours ago

(HealthDay)—The risk of hospitalized bacterial infections in older rheumatoid arthritis (RA) patients is similar for rituximab or abatacept compared to etanercept, although it is higher for infliximab, ...

New oral drug regimens cure hardest-to-treat hepatitis C

3 hours ago

Two new pill-only antiviral drug regimens could provide shorter, more effective treatment options with fewer side effects for the majority of patients infected with hepatitis C, even those most difficult to treat, according ...

User comments