Lung cancer risk unaffected by metformin use in diabetes
(HealthDay)—Patients with type 2 diabetes who take metformin do not have a reduced risk of lung cancer, in contrast to previous observational studies, according to a study published online Aug. 24 in Diabetes Care.
To determine whether metformin use in type 2 diabetes is associated with the incidence of lung cancer, Brielan B. Smiechowski, from the Jewish General Hospital in Montreal, and colleagues analyzed data from 115,923 patients with type 2 diabetes newly treated with oral hypoglycemic agents.
The researchers found that 1,061 patients were diagnosed with lung cancer during follow-up. Based on matching each lung cancer case with up to 10 matched control subjects, metformin had no effect on the lung cancer rate (rate ratio, 0.94). Smoking status had no effect. No dose-response was noted based on number of prescriptions received, cumulative duration of use, and cumulative dose.
"Metformin use is not associated with a decreased risk of lung cancer in patients with type 2 diabetes," Smiechowski and colleagues conclude. "The decreased risk reported in other observational studies is likely due to bias from methodological shortcomings."
More information: Abstract
Full Text (subscription or payment may be required)
Journal reference:
Diabetes Care
Copyright © 2012 HealthDay. All rights reserved.
-
Metformin may lower cancer risk in people with Type 2 diabetes
Jun 25, 2012 |
not rated yet |
0
-
Metformin may prevent lung cancer in smokers
Apr 19, 2010 |
not rated yet |
0
-
Diabetes linked to lung cancer in postmenopausal women
May 30, 2012 |
not rated yet |
0
-
Thiazolidinediones tied to lower cancer risk in diabetes patients
Apr 27, 2012 |
not rated yet |
0
-
Metformin appeared to slow prostate cancer growth
Apr 01, 2012 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Calculating on-axis elements of a solenoid
3 hours ago
-
latitude & longitude & air pressure
4 hours ago
-
Differences of Classical Mechanics when learned with Calc vs algebra?
7 hours ago
-
what is the distance traveled
11 hours ago
-
Image of a Convex Lens Cut in Half Horizontally
15 hours ago
-
Ray tracing throught optical system of thick lenses
15 hours ago
- More from Physics Forums - Classical Physics
More news stories
Fish oil supplements may help fight against Type 2 diabetes
Widely-used fish oil supplements modestly increase amounts of a hormone that is associated with lower risk of diabetes and heart disease, according to a study accepted for publication in The Endocrine Society's Journal of ...
Diabetes
10 hours ago |
5 / 5 (1) |
0
Study shows that women who smoke during pregnancy increase the risk of both obesity and gestational diabetes in their da
Women who smoke during pregnancy increase the risk of both obesity and gestational diabetes, in their daughters, concludes research published in Diabetologia, the journal of the European Association for the Study of Diabet ...
Diabetes
May 20, 2013 |
not rated yet |
0
Rise in type 2 diabetes amongst young
The number of young people diagnosed with type 2 diabetes has seen the sharpest rise over the last twenty years compared to a background of a general increase across the board, new University research has ...
Diabetes
May 20, 2013 |
not rated yet |
0
Research uncovers a potential role of two proteins in diabetes
(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.
Diabetes
May 20, 2013 |
5 / 5 (2) |
0
|
Exercise prevents fructose-induced hypertriglyceridemia
(HealthDay)—Moderate aerobic exercise prevents fructose-induced hypertriglyceridemia in healthy males, according to a study published online May 14 in Diabetes.
Diabetes
May 17, 2013 |
5 / 5 (1) |
0
|
Rate of bicycle-related fatalities significantly lower in states with helmet laws
Existing research shows that bicyclists who wear helmets have an 88 percent lower risk of brain injury, but researchers at Boston Children's Hospital found that simply having bicycle helmet laws in place showed a 20 percent ...
Slowing the aging process—only with antibiotics
Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.
Researchers complete largest genetic sequencing study of human disease
Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases.
Brain can be trained in compassion, study shows
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
Having both migraines, depression may mean smaller brain
(HealthDay)—Migraines and depression can each cause a great deal of suffering, but new research indicates the combination of the two may be linked to something else entirely—a smaller brain.
Novel approach for influenza vaccination shows promise in early animal testing
A new approach for immunizing against influenza elicited a more potent immune response and broader protection than the currently licensed seasonal influenza vaccines when tested in mice and ferrets. The vaccine ...