Mild cognitive decline in nearly half lacunar stroke patients

Mild cognitive decline in nearly half lacunar stroke patients
Mild cognitive impairment is present in nearly half of patients with lacunar stroke, according to a study published online Aug. 18 in the Annals of Neurology.

(HealthDay)—Mild cognitive impairment (MCI) is present in nearly half of patients with lacunar stroke, according to a study published online Aug. 18 in the Annals of Neurology.

Claudia Jacova, Ph.D., of the University of British Columbia in Vancouver, Canada, and associates conducted a study to characterize, and estimate the prevalence of, neuropsychological impairment in 1,636 English-speaking lacunar stroke patients. Using published norms, raw scores were converted to z scores. Participants underwent neuropsychological testing at baseline and those with impairment (z score of ≤1.5) in memory and/or non-memory domains were classified as having MCI.

The researchers found that the average z scores at baseline testing were below zero. The largest deficits were seen in measures of episodic memory (range of means, −0.65 to −0.92), (mean, −0.89), and motor dexterity (mean, −2.5). Of the participants, 47 percent were classified as having MCI, which included 36 percent amnestic, 37 percent amnestic multidomain, and 28 percent non-amnestic. Forty-one percent of those with Rankin score of 0 to 1 and Barthel score of 100 percent had MCI.

"In this large, well-characterized cohort of lacunar stroke patients, MCI was present in nearly half, including many with minimal or no physical disabilities," the authors write. " in lacunar may commonly be overlooked in clinical practice but may be as important as motor and sensory sequelae."

Study medication was donated by Sanofi/BMS USA.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Study: Men at higher risk for mild memory loss than women

Jan 25, 2012

Men may be at higher risk of experiencing mild cognitive impairment (MCI), or the stage of mild memory loss that occurs between normal aging and dementia, than women, according to a study published in the January 25, 2012, ...

Amnestic mild cognitive impairment doubles risk of death

Jul 16, 2012

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that people with a form of mild cognitive impairment (MCI), a risk factor for developing Alzheimer's disease, ...

Study finds mild cognitive impairment is more common in men

Sep 06, 2010

A new Mayo Clinic study found that the prevalence of mild cognitive impairment was 1.5 times higher in men than in women. The research, part of the Mayo Clinic Study of Aging, also showed a prevalence rate of 16 percent in ...

Recommended for you

Emotions in the brain

17 hours ago

This year has been a busy one for biologist David Anderson, Caltech's Seymour Benzer Professor of Biology. In 2014 alone, Anderson's lab has reported finding neurons in the male fly brain that promote fighting and, in the mouse brain, identified a "se ...

User comments