Multifactorial mechanisms underlie leg weakness in hip OA

Multifactorial mechanisms underlie leg weakness in hip OA
Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online July 25 in Arthritis Care & Research.

(HealthDay) -- Multiple factors contribute to leg weakness in people with hip osteoarthritis (OA), with muscle atrophy being the strongest contributor, according to the results of a systematic review published online July 25 in Arthritis Care & Research.

Aderson Loureiro, B.Phys.Ed., of the Griffith Health Institute in Gold Coast, Australia, and colleagues conducted a systematic review of 13 cross-sectional studies to determine whether leg muscle strength is affected in people with unilateral hip OA.

A review of the literature revealed strong evidence to suggest that the muscle strength of the leg affected with hip OA is weaker than that of the non-affected leg or that of healthy control legs. Moderate evidence indicated that the size and quality of the muscle is also affected by hip OA. Evidence for muscle inhibition within the affected limb of persons with hip OA was limited.

"The existing literature suggests unilateral hip OA is characterized by generalized muscle weakness of the affected limb. The mechanisms underlying muscle weakness are multifactorial, and include, in order based on strength and amount of available evidence, a combination of reduced muscle size (atrophy), muscle inhibition, and decreased muscle quality," the authors write. "Findings of this review suggest the need to address the issue of muscle weakness in the clinical management of hip OA."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Walking speed is a marker for knee osteoarthritis

Mar 20, 2012

(HealthDay) -- Slower walking speed may be a marker for identifying those at risk for knee osteoarthritis (OA), according to a study published online March 5 in Arthritis Care & Research.

Lower limb muscle limitations hamper walking in diabetes

May 30, 2012

(HealthDay) -- In older adults, diabetes correlates with slower walking speed, and diabetes-linked reductions in muscle strength and worse muscle quality contribute to these walking limitations, according ...

Recommended for you

Leptin may mediate knee-related osteoarthritis

Jan 28, 2015

(HealthDay)—The inflammatory adipokine leptin may have a mediating effect on the relationship between body weight and knee osteoarthritis (OA) in older adults, according to research published in the January ...

Cold effects on skin in raynaud's impacted by age, BMI

Jan 19, 2015

(HealthDay)—For patients with Raynaud's phenomenon (RP), cold-induced decrease in skin temperature is related to age and body mass index (BMI), according to a study published in the January issue of Arthritis & ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.