No increased risk of stroke after spinal fusion surgery

Jau-Ching Wu, M.D., from the National Yang-Ming University in Taiwan, and colleagues extracted data from a nationwide representative cohort of one million people, from 2000 to 2005, to examine the incidence and risk of stroke after spinal fusion surgery. Study participants included 2,249 spinal fusion surgery patients and 2,203 control subjects matched by age, sex, and propensity score; participants were followed for three years.

The researchers found that the incidence rates of any, hemorrhagic, and ischemic strokes were 9.95, 1.21, and 8.86, respectively, per 1,000 person-years in the spinal fusion group and 11.5, 1.69, and 9.93, respectively, in the control group. For patients who received spinal fusion surgery there was a decreased likelihood, which was not statistically significant, of any stroke (crude hazard ratio [HR], 0.87; P = 0.393), hemorrhagic stroke (HR, 0.72; P = 0.473), and ischemic stroke (HR, 0.89; P = 0.582), compared with the control group. The differences remained nonsignificant after adjustment for demographics, comorbidity, and medication use.

"The incidence of stroke after spinal fusion surgery was 10.7 per 1,000 person-years in this cohort study," the authors write. "Despite the lack of statistical significance, patients receiving spinal fusion surgery were less likely to have had any stroke in [the] three years post-operation."

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Journal reference: Spine Journal

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