New treatment available for repeated occlusion of arteries

New treatment available for repeated occlusion of arteries
A new endovascular brachytherapy procedure using liquid beta-emitting rhenium-188 is safe and effective in preventing restenosis in people with long-segment femoropopliteal in-stent stenosis, according to research published in the August issue of the Journal of Endovascular Therapy.

(HealthDay)—A new endovascular brachytherapy (EVBT) procedure using liquid beta-emitting rhenium-188 (Re-188) is safe and effective in preventing restenosis in people with long-segment femoropopliteal in-stent stenosis (ISS), according to research published in the August issue of the Journal of Endovascular Therapy.

Martin Werner, M.D., of Park Hospital in Leipzig, Germany, and colleagues conducted a study of 90 consecutive patients with symptomatic ISS/occlusion of the femoropopliteal segment who underwent angioplasty followed by a new EVBT method that uses liquid beta-emitting Re-188.

The researchers found the primary patency to be 95.2 percent at six months (follow-up of 88 patients) and 79.8 percent at 12 months (follow-up of 82 patients). One case of early and two cases of late acute thrombotic occlusions occurred. Nine patients experienced ISS and 10 patients experienced reocclusion of the treated segment. Overall clinical status improved for 67.0 and 62.2 percent at six and 12 months, respectively.

"In this study, the treatment of femoral ISS with beta radiation was safe and effective," the authors write. "Angioplasty in combination with EVBT resulted in a favorable primary patency rate of almost 80 percent and clinical improvement after 12 months. Most patients had non-focal patterns of ISS (diffuse, proliferative, or total occlusion) and would have been expected to respond poorly to angioplasty alone."

More information: Abstract
Full Text
Editorial

add to favorites email to friend print save as pdf

Related Stories

Results of the REMEDEE trial reported at TCT 2011

Nov 11, 2011

A randomized comparison of a dual therapy stent – which combines low-dose sirolimus delivery from an abluminal biodegradable polymer matrix with a covalently bound anti-CD34 antibody layer – with a paclitaxel-eluting ...

Recommended for you

Barriers preventing post-stroke care

17 hours ago

For stroke victims, rehabilitation is crucial to their recovery. But a Flinders University study conducted in Singapore found that rehabilitation rates following discharge from hospital are poor because of gaps in the continuum ...

Home-based rehabilitation for CVD patients

18 hours ago

Patients who are found to suffer from cardiovascular diseases often have long years of treatment ahead of them and are urged to drastically change their lifestyle. But what is probably the most difficult ...

New remote patient monitoring devices available

21 hours ago

(HealthDay)—Several new remote patient monitoring devices with useful applications are available or under development, according to an article published July 8 in Medical Economics.

Monitoring pulse after stroke may prevent a second stroke

Jul 23, 2014

New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of ...

User comments