Arterial stiffness inversely tied to plasma adiponectin levels

September 27, 2012
Arterial stiffness inversely tied to plasma adiponectin levels
Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

(HealthDay)—Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

By measuring carotid-femoral pulse wave velocity (PWV), Afroditi Tsiakou, M.D., from the Athens University Medical School in Greece, and colleagues assessed large artery stiffness in normotensive patients with up to the age of 40.

The researchers found that the 80 patients (39 men) who were included in the analysis were characterized as having an age of 27.1 ± 6.1 years; a of 24.2 ± 3.1 kg/m²; a glycated of 7.5 ±1.6 percent; an adiponectin level of 13.9 ± 6.7 µg/mL; and PWV of 5.6 ± 0.9 m/s. There was a significant, inverse correlation of log adiponectin with age-adjusted PWV and .

"Arterial stiffness is inversely related to adiponectin concentration in young patients with type 1 diabetes without major complications," the authors write. "Future studies may assess adiponectin at diagnosis of diabetes and after cardiovascular events, while randomized trials could target increasing adiponectin in patients with type 1 diabetes and low adiponectin."

Explore further: Another potential risk factor for developing dementia and Alzheimer's disease in women

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Metabolic syndrome linked to arterial stiffness in CKD

June 4, 2012

(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to ...

Nutrition type affects endocrinology in SGA infants

August 1, 2012

(HealthDay) -- Small-for-gestational-age (SGA) infants who are formula-fed (FOF) have elevated endocrine levels of high-molecular-weight (HMW) adiponectin and insulin growth factor-I (IGF-I) compared with breastfed (BRF) ...

Recommended for you

Engineered hot fat implants reduce weight gain in mice

August 20, 2015

Scientists at the University of California, Berkeley, have developed a novel way to engineer the growth and expansion of energy-burning "good" fat, and then found that this fat helped reduce weight gain and lower blood glucose ...

Promising progress for new treatment of type 1 diabetes

July 30, 2015

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports, reveals that administration ...

Bacteria may cause type 2 diabetes

June 1, 2015

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.