Genetic counseling doesn't affect pre-diabetes behavior

Genetic counseling doesn't affect pre-diabetes behavior
Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

(HealthDay)—Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

Richard W. Grant, M.D., M.P.H., from Kaiser Permanente Northern California in Oakland, and colleagues conducted a randomized trial in which 108 overweight patients (mean age, 57.9 years) at increased phenotypic risk for type 2 diabetes were assigned to receive genetic testing or not. Thirty-six were used to assess genetic risk. Individual was provided to participants in the top (42 participants) and bottom (32 participants) score quartiles prior to being enrolled, together with 34 untested controls, in a 12-week validated diabetes prevention program. Middle-risk quartile participants were not included in the study.

The researchers found that participants attended 6.8 ± 4.3 group sessions and lost 8.5 ± 10.1 pounds, with 30.6 percent of participants losing ≥5 percent body weight. Comparing higher-risk recipients and lower-risk recipients with control subjects who did not receive counseling, there were few statistically significant differences in self-reported motivation, program attendance, or mean weight loss.

"In summary, a diabetes genetic risk assessment and counseling intervention for based on 36 single nucleotide polymorphisms neither improved nor substantially detracted from an evidence-based behavioral intervention to prevent diabetes," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Blood glucose levels set for achieving HbA1c targets

Apr 11, 2014

(HealthDay)—The average self-monitored blood glucose (SMBG) concentrations needed at premeal, postmeal, and bedtime have been established to achieve a range of hemoglobin A1c (HbA1c) targets, according ...

Women with diabetes less likely to have a mammogram

Apr 11, 2014

Women with diabetes are 14 per cent less likely to be screened for breast cancer compared to women without diabetes, according to a study by researchers at the Institute for Clinical Evaluative Sciences (ICES) and Women's ...

Nonalcoholic fatty liver disease linked to CKD in T1DM

Apr 09, 2014

(HealthDay)—For patients with type 1 diabetes, nonalcoholic fatty liver disease (NAFLD) is independently associated with the risk of incident chronic kidney disease (CKD), according to a study published ...

Common diabetes treatment could extend hypoglycaemia

Apr 08, 2014

(Medical Xpress)—Researchers at the University of Adelaide have discovered that a common treatment for people with type 2 diabetes could cause longer-than-normal periods of the low blood sugar reaction hypoglycaemia, which ...

User comments