Genetic counseling doesn't affect pre-diabetes behavior

September 7, 2012
Genetic counseling doesn't affect pre-diabetes behavior
Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

(HealthDay)—Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

Richard W. Grant, M.D., M.P.H., from Kaiser Permanente Northern California in Oakland, and colleagues conducted a randomized trial in which 108 overweight patients (mean age, 57.9 years) at increased phenotypic risk for type 2 diabetes were assigned to receive genetic testing or not. Thirty-six were used to assess genetic risk. Individual was provided to participants in the top (42 participants) and bottom (32 participants) score quartiles prior to being enrolled, together with 34 untested controls, in a 12-week validated diabetes prevention program. Middle-risk quartile participants were not included in the study.

The researchers found that participants attended 6.8 ± 4.3 group sessions and lost 8.5 ± 10.1 pounds, with 30.6 percent of participants losing ≥5 percent body weight. Comparing higher-risk recipients and lower-risk recipients with control subjects who did not receive counseling, there were few statistically significant differences in self-reported motivation, program attendance, or mean weight loss.

"In summary, a diabetes genetic risk assessment and counseling intervention for based on 36 single nucleotide polymorphisms neither improved nor substantially detracted from an evidence-based behavioral intervention to prevent diabetes," the authors write.

Explore further: Waist circumference linked to diabetes risk, independently of body mass index

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Experimental drug helps diabetes patients lose weight

June 25, 2012

An experimental drug helped significantly more overweight patients with diabetes shed pounds, compared with placebo, a new study finds. The results will be presented at The Endocrine Society's 94th Annual Meeting in Houston.

Recommended for you

Low-carb diet may aid your metabolism

December 2, 2016

(HealthDay)—Eating low-carbohydrate meals may lead to healthy changes in a woman's metabolism that don't occur when consuming higher-carbohydrate meals, a small study suggests.

Research shows nerve growth protein controls blood sugar

November 14, 2016

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.