HIV treatment use increases in the US
Between 2000 and 2008, the proportion of HIV-infected patients in the U.S. receiving effective treatment known as highly active antiretroviral therapy (HAART) increased, and HIV-infected patients appeared to be less infectious and have healthier immune systems at death, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. The study was nested in the NA-ACCORD (North American AIDS Cohort Collaboration on Research and Design), which is the largest cohort of HIV-infected adults in North America. The findings are published in the September 4 edition of Annals of Internal Medicine.
The study included more than 45,000 HIV-infected participants receiving clinical care for HIV. The study population was demographically similar to the U.S. population living with HIV, according to national surveillance data from the Centers for Disease Control and Prevention. Over the study period, the researchers found that the proportion of HIV-infected participants prescribed HAART increased 9 percentage points to 83 percent. During this time, the researchers also observed an increase in viral load suppression among those with HIV, regardless of treatment. Suppression of viral load reduces the likelihood of transmitting HIV to others. Among those taking HAART, the proportion with a suppressed viral load increased from 54 percent to 81 percent.
"This is good news for the HIV epidemic in the U.S., but there is room for improvement," said Keri N. Althoff, PhD, MPH, lead author of the study and assistant professor in the Bloomberg School's Department of Epidemiology. "We need to continue to focus on linking HIV-infected adults into care and effective treatment, not only for the individual's health, but to reduce the likelihood of transmission to others."
The analysis also found an increase in median CD4 count for participants who died from HIV during the study period. Median counts increased at the time of death from 60 cells/mm3 to 209 cells/mm3. A higher CD4 count suggests a healthier immune system. Additional research is planned to investigate trends in the causes of death.
"Our study demonstrates the data from the NA-ACCORD can be used to monitor important health indicators among adults with HIV, which is needed to evaluate the impact of the Affordable Care Act and to measure progress towards the National HIV Strategy goals," said Althoff.
More information: U.S. Trends in Antiretroviral Therapy Use, HIV RNA Plasma Viral Loads, and CD4 T-Lymphocyte Cell Counts among HIV-infected Persons, 2000 to 2008, Annals of Internal Medicine, 2012.
Journal reference: Annals of Internal Medicine
- Many with HIV start care too late May 28, 2010 | not rated yet | 0
- Study examines cost-effectiveness of HIV monitoring strategy in countries with limited resources Sep 22, 2008 | not rated yet | 0
- Study finds HIV-infected men at risk for spreading HIV despite taking HAART Mar 27, 2012 | not rated yet | 0
- Revaccination could benefit HIV-infected children Sep 01, 2010 | not rated yet | 0
- Only 1 in 4 americans with HIV has virus under control: CDC Jul 27, 2012 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
(HealthDay)—For HIV-infected individuals with recurrent Clostridium difficile infection, fecal microbiota therapy is feasible, according to a letter published in the May 21 issue of the Annals of Intern ...
HIV & AIDS 13 hours ago | not rated yet | 0
Canadian health authorities lifted Wednesday what was effectively a ban on gay men giving blood, announcing new rules making men who have not had sex with men in the past five years eligible.
HIV & AIDS 15 hours ago | not rated yet | 1
Top AIDS scientists were optimistic Wednesday of finding a cure for the disease that has claimed 30 million lives—but said it might not work for all people.
HIV & AIDS 18 hours ago | not rated yet | 0
The integration of mental health interventions into HIV prevention and treatment platforms can reduce the opportunity costs of care and improve treatment outcomes, argues a new Policy Forum article published in this week's ...
HIV & AIDS May 21, 2013 | not rated yet | 0
US teen births have dropped to a record low, but the country still has one of the highest rates among developed nations, the US Centers for Disease Control and Prevention said Thursday.
1 hour ago | not rated yet | 0
Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.
18 hours ago | 4.9 / 5 (9) | 1 |
Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases.
18 hours ago | 4.7 / 5 (3) | 0 |
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
15 hours ago | 5 / 5 (2) | 2 |
Existing research shows that bicyclists who wear helmets have an 88 percent lower risk of brain injury, but researchers at Boston Children's Hospital found that simply having bicycle helmet laws in place showed a 20 percent ...
7 hours ago | not rated yet | 0
(HealthDay)—Migraines and depression can each cause a great deal of suffering, but new research indicates the combination of the two may be linked to something else entirely—a smaller brain.
15 hours ago | 4.3 / 5 (3) | 0 |