Insulin sensitivity lower in adults born preterm

Insulin sensitivity lower in adults born preterm
Middle-aged adults who were born preterm, even moderately preterm (32 to 36 weeks' gestation), are less insulin sensitive compared with adults who were born at term, according to research published in the October issue of Diabetes.

(HealthDay)—Middle-aged adults who were born preterm, even moderately preterm (32 to 36 weeks' gestation), are less insulin sensitive compared with adults who were born at term, according to research published in the October issue of Diabetes.

Sarah Mathai, M.D., of the University of Auckland in New Zealand, and colleagues conducted a study involving 52 adults aged 34 to 38 years (31 had been born preterm) and 61 of their children (37 born of preterm parents) to evaluate whether there is a relationship between insulin sensitivity and β-cell function in adults born preterm and their children.

The researchers found that, compared with adults born at term, those born preterm were less insulin sensitive, regardless of sex. This association remained even after excluding those who had been born prior to 32 weeks' gestation. β-cell function was normal in these adults. However, children born to adults who were preterm did not display .

"In conclusion, adults born even moderately preterm (32 to 36 weeks' gestation) have an isolated reduction in insulin sensitivity but normal β-cell function. There was no evidence of impaired in their children," the authors write. "Because the rate of preterm birth is rising, with the majority born only moderately preterm, the associated reduced in adults born preterm is likely to pose a substantial burden in the future."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Preterm birth rate drops

Mar 18, 2009

The nation's preterm birth rate declined slightly in 2007 - a finding that the March of Dimes hopes will prove to be the start of a new trend in improved maternal and infant health.

Recommended for you

Screening for diabetes at dental visits using oral blood

Feb 26, 2015

It is estimated that 8.1 million of the 29.1 million Americans living with diabetes are undiagnosed and many who have diabetes have poor glycemic control. Given that each year many Americans visit a dental provider but not ...

CBT, sertraline insufficient in diabetes and depression

Feb 26, 2015

(HealthDay)—For patients with diabetes and depression, improvements in depression are seen with cognitive behavioral therapy (CBT) or sertraline, with a significant advantage for sertraline, but glycemic ...

Early signs in young children predict type 1 diabetes

Feb 26, 2015

New research shows that it is possible to predict the development of type 1 diabetes. By measuring the presence of autoantibodies in the blood, it is possible to detect whether the immune system has begun to break down the ...

Daily menu plan reduces blood sugar significantly

Feb 25, 2015

A large group of people with diabetes who followed a menu plan created by University of Alberta nutrition researchers for just three months significantly reduced their blood sugar levels.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.