Merck KGaA suffers setback for cancer drug

September 18, 2012

German pharmaceuticals maker Merck KGaA said Tuesday it is withdrawing its application for its drug Erbitux to be used to treat patients with lung cancer.

Merck said in a statement it had decided to "voluntarily withdraw the marketing authorisation application to the European Medicines Agency" for to be used to treat patients with advanced or metastatic non-small cell lung cancer.

The decision was "based on feedback from European regulatory authorities, indicating that further data would be required," the statement said.

It would not affect, however, "the proven utility of Erbitux in its already approved indications in metastatic and ," Merck insisted.

"We are disappointed that we have not been able to move forward with the filing but it has become apparent that further data will be required to support the clinical utility of Erbitux in this specific population," said Merck's head of drug development, Annalisa Jenkins.

Already in July, Merck KGaA had said that phase III clinical trials of Erbitux for treatment of drug had shown no benefits of the drug for patients.

The news hit Merck KGaA shares which were showing a loss of 1.24 percent at 93.67 euros in mid-morning trade on the Frankfurt stock exchange in a generally softer market.

Explore further: Merck KGaA suffers setback on cancer drug

Related Stories

Merck KGaA suffers setback on cancer drug

July 5, 2012

German pharmaceuticals maker Merck KGaA said Thursday that phase III clinical trials of its gastric cancer drug Erbitux had shown no benefits for patients.

New test helps evaluate cancer drug's merit

July 9, 2012

(HealthDay) -- A new genetic test to help doctors determine if the drug Erbitux would be an effective treatment for certain colorectal cancer patients has been approved by the U.S. Food and Drug Administration.

Recommended for you

Combination therapy can prevent cytostatic resistance

November 26, 2015

Researchers at Karolinska Institutet have found a new way of preventing resistance to cytostatics used in the treatment of cancers such as medulloblastoma, the most common form of malignant brain tumour in children. The promising ...

Forecasting the path of breast cancer in a patient

November 23, 2015

USC researchers have developed a mathematical model to forecast metastatic breast cancer survival rates using techniques usually reserved for weather prediction, financial forecasting and surfing the Web.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.