A sad legacy—Victims of childhood asbestos exposure

September 4, 2012 in Cancer

A sad legacy--Victims of childhood asbestos exposure

1953--four-year-old neighbours playing in an asbestos sandpit in a residential backyard in Wittenoom.  Residents purchased the deadly tailings which were commonly used as sandpits in backyards for the purposes of children's play and also to reduce dust around houses.  Philip Noble (left) grew up to be a keen footballer before dying from mesothelioma at 36.  Ross Munroe (right) became a High School Principal and died from mesothelioma at 38. Credit: Asbestos Diseases Society of Australia Inc.

(Medical Xpress)—"Wittenoom kids" who spent their childhoods exposed to asbestos in the north-west of Western Australia are now developing a range of cancers or dying at a rate well above the average population, according to a new study by researchers from The University of Western Australia for the UWA-affiliated Western Australian Institute for Medical Research (WAIMR). 

Mining of the deadly blue asbestos at Wittenoom, 1106km north of Perth, ceased in 1966 and the town was later closed after airborne fibres in dust from mining operations were found to cause , , and other serious diseases.

While data has been collected previously looking at asbestos-related diseases caused by occupational among men (either working in asbestos mining towns or using asbestos products), this new study is the first to look at the long-term health of children who were exposed to asbestos at Wittenoom.

The study, which has been published in the , shows that girls up to the age of 15 who lived in Wittenoom have been more likely to develop mesothelioma, ovarian and brain cancers and have had increased .

Boys who spent their childhood and early teenage years in Wittenoom during the years that asbestos was mined (1943-1966) now have elevated rates of mesothelioma, leukaemia, prostate, brain and , diseases of the circulatory and nervous system, and excessive death  rates.

"The original township was only 1.6km from the mine," said leading researcher on the paper, WAIMR's Associate Professor Alison Reid.  "Later in 1947, when the population grew, the township was moved 12km away from the mine site but tailings from the mine were used throughout the town.

"These tailings, rich in crocidolite fibres, were used to pave roads, footpaths, parking areas, the local racecourse and school playgrounds.  They were even used in people's backyards, where, of course, children often played," she said. "These "Wittenoom kids" are now reaching the age where chronic adult diseases are becoming more prevalent and many have died." 

Associate Professor Reid said the study by WAIMR researchers from UWA's School of Population Health found that a total of 2460 former Wittenoom children were documented to have been exposed to blue asbestos before the age of 15.

The median age of their first exposure was at three years of age.

Of the people studied, 63 per cent were either born in Wittenoom or had moved to the mining town by the time they were three years old.  The vast majority (93.5 per cent) left Wittenoom by the time they were 16, so were exposed to asbestos only during their childhoods.

By the end of 2007, 228 former residents had died from a range of causes.  By the end of 2009, there were 215 cases of cancer in 207 individuals.

This means that compared with the general population in Western Australia, Wittenoom girls have had a 20-47 per cent greater risk of dying from any cause, while boys have had a 50-83 per cent increased chance of dying from any cause.

"We will continue to follow this group to provide important information on the long-term implications of exposure to during childhood," Associate Professor Alison Reid said.

Provided by University of Western Australia search and more info website

not rated yet  

Filter


Move the slider to adjust rank threshold, so that you can hide some of the comments.


Display comments: newest first

Tom_Hennessy
Sep 04, 2012

Rank: 1 / 5 (2)
They've shown the iron found on asbestos is what causes the problems.

"Asbestos-associated catalytic iron, whether constitutional or induced by other mechanisms, plays an important role in asbestos-induced carcinogenesis and that chemoprevention may be possible through targeting the catalytic iron"

Phytic acid , found in our food , is an iron chelator , binds up iron stopping it from 'rusting' / oxidising and phytic acid has been shown to affect asbestos.

"We show that asbestos augments p53 expression in cells at the bronchoalveolar duct junctions of rat lungs and that phytic acid prevents this."
Rank not rated yet
Relevant PhysicsForums posts

More news stories

American cancer society celebrates 100 years of progress

(HealthDay)—The American Cancer Society, which is celebrating on Wednesday a century of fighting a disease once viewed as a death sentence, is making a pledge to put itself out of business.

Cancer created 10 hours ago | popularity not rated yet | comments 0

CT detects twice as many lung cancers as X-ray at initial screening exam

National Lung Screening Trial (NLST) investigators also conclude that the 20 percent reduction in lung cancer mortality with low-dose computed tomography (LDCT) versus chest X-ray (CXR) screening previously reported in the ...

Cancer created 10 hours ago | popularity not rated yet | comments 0

Research offers promising new approach to treatment of lung cancer

Researchers have developed a new drug delivery system that allows inhalation of chemotherapeutic drugs to help treat lung cancer, and in laboratory and animal tests it appears to reduce the systemic damage ...

Cancer created 14 hours ago | popularity not rated yet | comments 0 | with audio podcast

Study details genes that control whether tumors adapt or die when faced with p53 activating drugs

When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumors die – the rest resist the challenge. A study published in the journal Cell Reports shows how: tumors that live even i ...

Cancer created 14 hours ago | popularity not rated yet | comments 0 | with audio podcast

Small increase in cancer risk following CT scans in childhood and adolescence

Study leader, Professor John Mathews from the University of Melbourne said this small increase in cancer risk must be weighed against the undoubted benefits from CT scans in diagnosing and monitoring disease.

Cancer created 18 hours ago | popularity not rated yet | comments 0


Slowing the aging process—only with antibiotics

Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.

Rate of bicycle-related fatalities significantly lower in states with helmet laws

Existing research shows that bicyclists who wear helmets have an 88 percent lower risk of brain injury, but researchers at Boston Children's Hospital found that simply having bicycle helmet laws in place showed a 20 percent ...

Researchers complete largest genetic sequencing study of human disease

Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases.

Brain can be trained in compassion, study shows

Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.

Having both migraines, depression may mean smaller brain

(HealthDay)—Migraines and depression can each cause a great deal of suffering, but new research indicates the combination of the two may be linked to something else entirely—a smaller brain.

Novel approach for influenza vaccination shows promise in early animal testing

A new approach for immunizing against influenza elicited a more potent immune response and broader protection than the currently licensed seasonal influenza vaccines when tested in mice and ferrets. The vaccine ...