More antibiotic use tied to rise in diarrheal infections in hospitals, study finds

More antibiotic use tied to rise in diarrheal infections in hospitals: study
Kids, elderly especially vulnerable to serious consequences from C. difficile bacteria.

(HealthDay)—Greater use of antibiotics is the main reason for an increase in the number and severity of Clostridium difficile infections among hospitalized children and elderly people, researchers report.

This type of bacteria is the most common cause of in hospitals and is linked to 14,000 deaths in the United States each year.

For the study, Mayo Clinic researchers analyzed national data from about 13.7 million children who were hospitalized over a five-year period and found that the more than 46,000 with C. difficile infections had much longer hospital stays, were more likely to require partial or total removal of the colon, were more likely to be admitted to long- or short-term care facilities and had a higher risk of death.

"Despite increased awareness of C. difficile in children, and advancements in management and prevention, this remains a major problem in hospitalized children," gastroenterologist Dr. Sahil Khanna, said in a Mayo Clinic news release.

The researchers also looked at data from 1.3 million hospitalized adults with C. difficile infections and found that those over 65 spent more time in the hospital, were more likely to be sent to a nursing home and had a greater risk of death.

These findings suggest that being over age 65 is an for poorer outcomes among adults with C. difficile infection, the researchers said.

The study authors said that greater is the main reason for the growing number of C. difficile infections. This is because antibiotics destroy the that protect against infections.

The study was scheduled for presentation at the American College of Gastroenterology's annual meeting in Las Vegas. The data and conclusions of research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

More information: The U.S. Centers for Disease Control and Prevention has more about C. difficile infection.

add to favorites email to friend print save as pdf

Related Stories

C. difficile and antibiotics not necessarily linked

Oct 07, 2008

The latest study by Dr. Sandra Dial from the Research Institute of the MUHC, McGill University, and Attending Staff in the Intensive Care Unit at the Jewish General Hospital, questions the assumption held by a vast majority ...

Recommended for you

Nigeria records two new cases of Ebola

7 minutes ago

Nigeria on Friday said that two more people had tested positive for Ebola, taking the total number of confirmed cases of the deadly virus in the country to 14, including five deaths.

Senegal closes border as UN warns on Ebola flare-up

4 hours ago

Senegal has become the latest country to seal its border with a west African neighbour to ward off the deadly Ebola virus, as the new UN pointman on the epidemic said preparations must be made for a possible flare-up of the ...

Climate change could see dengue fever come to Europe

4 hours ago

Dengue fever could make headway in popular European holiday destinations if climate change continues on its predicted trajectory, according to research published in open access journal BMC Public Health.

American Ebola doc: 'I am thrilled to be alive'

12 hours ago

Calling it a "miraculous day," an American doctor infected with Ebola left his isolation unit and warmly hugged his doctors and nurses on Thursday, showing the world that he poses no public health threat ...

User comments