Asia battles drug-resistant malaria

October 31, 2012 by Madeleine Coorey

Drug-resistant malaria is spreading in Asia, experts warned as a high-level conference opened Wednesday with the aim of hammering out an action plan to strengthen the region's response.

Resistance to the drug used everywhere to cure the life-threatening disease has emerged in Cambodia, Thailand and Myanmar, said Richard Feachem, director of at the University of California, San Francisco.

"In the Mekong Basin there is a growing and spreading problem of resistance... to the drug artemisinin which is the frontline drug worldwide," he said ahead of " 2012: Saving Lives in the Asia-Pacific" in Sydney.

"I think we've undoubtedly slowed it down, the international efforts have undoubtedly had a positive effect, but as far as we can tell it is still growing and it is still spreading.

"The danger is that at some time this resistance may break out of Southeast Asia and crop up in Africa," added Feachem, the former founding head of the Global Fund to Fight AIDS, Tuberculosis and Malaria.

Some 22 countries in the Asia-Pacific still have malaria, but enormous progress has been made in combatting the devastating disease with the number of infections falling by about 50 percent in the past decade, he said.

Yet there were still an estimated 30 million cases in the Asia-Pacific in 2010, and more than 40,000 deaths in and the Western Pacific, according to the (WHO).

Drug- was found on the Thailand-Cambodia border eight years ago, and has also been found along the Thailand-Myanmar frontier and in parts of Vietnam, prompting an urgent call for action from the WHO in September.

The Sydney conference of politicians, scientists and will seek consensus on the actions needed to strengthen the region's response to malaria.

Fatoumata Nafo-Traore, who leads the Partnership which aims to provide a coordinated global approach to fighting the disease, said the resistance was most troubling in border areas.

"The current concern is that even though it is localised in those border areas, there is a potential to have it spreading to other parts of the world, because of the population inflow, because of the migrant workers and so on," she told AFP.

"This is really why we are getting concerned, because this is the only class of anti-malarial drug available to cure all uncomplicated malaria cases."

Resistance to artemisinin currently does not prevent patients being cured, thanks to other drugs it is used in concert with, but treatment typically takes longer than normal.

It is not known why the resistance has emerged in Cambodia, one of the first countries to deploy the treatment some 30 years ago.

But Ric Price, from the Centre of Tropical Medicine at Oxford in Britain, said high levels of counterfeit drugs and people not taking the full course of treatment could be factors.

" still remains the treatment of choice but it's under threat and we have to monitor where those areas are, where it is declining," he said.

The conference will discuss the need for vigilance against malaria, with Feachem saying there had been numerous cases in the past when the disease had almost been eradicated but complacency saw it come sweeping back.

"It's the penalty of success," he said. "Some countries in the region now have very little malaria. When you're down to 100 cases a year, the politicians (lose interest) and malaria comes surging back."

He said one of the conference goals was for half of the malaria-afflicted countries in the Asia-Pacific to eradicate the disease by 2025.

"That would be a huge historic step forward," he said.

Malaria is a life-threatening disease caused by parasites that are transmitted through the bites of infected mosquitoes. It killed an estimated 655,000 people in 2010, mostly African children.

Explore further: WHO hopeful drug-resistant malaria can be contained

Related Stories

WHO hopeful drug-resistant malaria can be contained

April 24, 2012

The World Health Organisation said Tuesday it was optimistic drug-resistant malaria that has emerged along Thailand's borders with Cambodia and Myanmar could be contained within the region.

WHO urges action as drug-resistant malaria spreads

September 27, 2012

The World Health Organization said Thursday that governments in the Mekong region must act "urgently" to stop the spread of drug-resistant malaria which has emerged in parts of Vietnam and Myanmar.

Fake malaria drugs a growing problem: experts

December 5, 2011

Fake or poor quality malaria drugs are boosting resistance in parts of southeast Asia, a problem that is likely to worsen unless tighter regulations are adopted, US experts said Monday.

Recommended for you

Zika virus infection alters human and viral RNA

October 20, 2016

Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications—chemical tags known as ...

Food-poisoning bacteria may be behind Crohn's disease

October 19, 2016

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn's disease later in life, according to a new study led by researchers at McMaster University.

Neurodevelopmental model of Zika may provide rapid answers

October 19, 2016

A newly published study from researchers working in collaboration with the Regenerative Bioscience Center at the University of Georgia demonstrates fetal death and brain damage in early chick embryos similar to microcephaly—a ...

Scientists uncover new facets of Zika-related birth defects

October 17, 2016

In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute (TSRI) have elucidated how the virus attacks the brains of newborns, ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.