Differences in sepsis care identified in europe, U.S.

Differences in sepsis care identified in europe, U.S.
Despite differences in processes of care and raw mortality for patients with severe sepsis and septic shock in the United States and Europe, after adjustment, mortality rates are similar, according to a study published online Oct. 26 in The Lancet Infectious Diseases.

(HealthDay)—Despite differences in processes of care and raw mortality for patients with severe sepsis and septic shock in the United States and Europe, after adjustment, mortality rates are similar, according to a study published online Oct. 26 in The Lancet Infectious Diseases.

Mitchell M. Levy, M.D., from the Warren Alpert Medical School of Brown University in Providence, R.I., and colleagues compared models of care and outcomes for 25,375 patients with severe sepsis and septic shock, entered into the Surviving Sepsis Campaign database from Europe (79 hospital sites with 6,609 patients) and the United States (107 units with 18,766 patients).

The researchers found that, in the United States, 65.1 percent of patients were admitted to the (ICU) from emergency departments, while in Europe, 51.5 percent of patients were admitted from hospital wards. In Europe, the median stay on the hospital wards before ICU admission was longer than in the United States (1.0 versus 0.1 days). In Europe, there was a longer median length of stay in the ICU (7.8 versus 4.2 days) and the hospital (22.8 versus 10.5 days). Raw hospital mortality was increased in Europe versus the United States (41.1 versus 28.3 percent), but adjusted mortality was not significantly different (32.3 and 31.3 percent, respectively; P = 0.468). The United States exhibited higher complete compliance with all applicable elements of the resuscitation bundle (21.6 versus 18.4 percent).

"The significant difference in unadjusted mortality and the fact that this difference disappears with severity adjustment raise important questions about the effect of the approach to critical care in Europe compared with that in the U.S.A.," the authors write.

Two authors disclosed financial ties to pharmaceutical and medical equipment companies, including and Philips Medical Systems, both of which partially funded the study.

More information: Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Sepsis campaign improving treatment of major killer

Jan 13, 2010

A reduction in hospital mortality from severe sepsis and septic shock was associated with participation in the Surviving Sepsis Campaign performance improvement initiative, according to an article published simultaneously ...

Recommended for you

Presence of peers ups health workers' hand hygiene

10 hours ago

(HealthDay)—The presence of other health care workers improves hand hygiene adherence, according to a study published in the October issue of Infection Control and Hospital Epidemiology.

Sierra Leone streets deserted as shutdown begins

18 hours ago

Sierra Leone's normally chaotic capital resembled a ghost town on Friday as residents were confined to their homes for the start of a three-day lockdown aimed at halting the deadly Ebola epidemic.

Sierra Leone launches controversial Ebola shutdown

20 hours ago

Sierra Leone on Friday launched a controversial three-day shutdown to contain the deadly spread of the Ebola virus, as the UN Security Council declared the deadly outbreak a threat to world peace.

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

Eikka
not rated yet Oct 27, 2012
So, what are they saying in plain english?

41.1% hospital mortality rate seems rather high. Surely not 2/5 of the patients leave a hospital dead?