Differences in sepsis care identified in europe, U.S.

Differences in sepsis care identified in europe, U.S.
Despite differences in processes of care and raw mortality for patients with severe sepsis and septic shock in the United States and Europe, after adjustment, mortality rates are similar, according to a study published online Oct. 26 in The Lancet Infectious Diseases.

(HealthDay)—Despite differences in processes of care and raw mortality for patients with severe sepsis and septic shock in the United States and Europe, after adjustment, mortality rates are similar, according to a study published online Oct. 26 in The Lancet Infectious Diseases.

Mitchell M. Levy, M.D., from the Warren Alpert Medical School of Brown University in Providence, R.I., and colleagues compared models of care and outcomes for 25,375 patients with severe sepsis and septic shock, entered into the Surviving Sepsis Campaign database from Europe (79 hospital sites with 6,609 patients) and the United States (107 units with 18,766 patients).

The researchers found that, in the United States, 65.1 percent of patients were admitted to the (ICU) from emergency departments, while in Europe, 51.5 percent of patients were admitted from hospital wards. In Europe, the median stay on the hospital wards before ICU admission was longer than in the United States (1.0 versus 0.1 days). In Europe, there was a longer median length of stay in the ICU (7.8 versus 4.2 days) and the hospital (22.8 versus 10.5 days). Raw hospital mortality was increased in Europe versus the United States (41.1 versus 28.3 percent), but adjusted mortality was not significantly different (32.3 and 31.3 percent, respectively; P = 0.468). The United States exhibited higher complete compliance with all applicable elements of the resuscitation bundle (21.6 versus 18.4 percent).

"The significant difference in unadjusted mortality and the fact that this difference disappears with severity adjustment raise important questions about the effect of the approach to critical care in Europe compared with that in the U.S.A.," the authors write.

Two authors disclosed financial ties to pharmaceutical and medical equipment companies, including and Philips Medical Systems, both of which partially funded the study.

More information: Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Sepsis campaign improving treatment of major killer

Jan 13, 2010

A reduction in hospital mortality from severe sepsis and septic shock was associated with participation in the Surviving Sepsis Campaign performance improvement initiative, according to an article published simultaneously ...

Recommended for you

Hong Kong makes Ebola 'contingency' measures

2 hours ago

Hong Kong said Wednesday it was quarantining all people from Guinea, Sierra Leone and Liberia who were showing Ebola-like symptoms on arrival in the city, as fears grow worldwide about the spread of the deadly virus.

EU ready for Ebola threat: sources

5 hours ago

The European Union is equipped and ready to treat victims should the deadly Ebola virus, which has killed hundreds in West Africa, be found in member states, EU sources said Wednesday.

Reducing kidney injury using a quality improvement method

9 hours ago

Using quality improvement measures in eight of the 10 hospitals in the Northern New England Cardiovascular Disease Study Group, researchers have found a way to reduce kidney injury in patients undergoing a procedure with ...

App for headache sufferers shows success

22 hours ago

A unique app that helps headache sufferers to record the severity and regularity of their pain is being used as part of a Griffith research study.

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

Eikka
not rated yet Oct 27, 2012
So, what are they saying in plain english?

41.1% hospital mortality rate seems rather high. Surely not 2/5 of the patients leave a hospital dead?