Obese teens face higher risk for kidney disease: study
Extra weight has real health consequences, but losing pounds can lower chances, expert says.
(HealthDay)—Obese and overweight teens may be at higher risk for developing advanced kidney disease as adults, Israeli researchers report.
If, however, they lose weight their chances may be lowered, experts say.
"This study comes as close as one can to predicting that losing weight can reduce the risk of kidney disease," said Dr. Kirsten Johansen, a professor in the division of nephrology at the University of California, San Francisco.
Johansen, who wrote an accompanying editorial with the study, said that "this gives us one more reason we need to address childhood obesity and overweight, but it's hard to do."
Johansen, however, is optimistic. "The rate of obesity and overweight has gone up quickly in our kids. If we can turn this around, it could go down quickly as well," she said. "I'm not saying it's easy. It's easier to get kids to drink soda than eat vegetables."
The report was published online Oct. 29 in the Archives of Internal Medicine.
For the study, a team led by Dr. Asaf Vivante, of the Edmond and Lily Safra Children's Hospital, Sheba Medical Center in Tel Hashomer, collected data on almost 1.2 million 17-year-olds who were examined before service in the Israeli military between January 1967 and December 1997. The researchers then linked these teens to the Israeli end-stage kidney disease registry.
Over 30 years of follow-up, they found more than 700 men and 160 women developed end-stage kidney disease.
Vivante's group estimated being overweight or obese and being treated for diabetes increased the risk of developing end-stage kidney disease. The risk was increased sixfold for those who were overweight and 19 times for those who were obese, the researchers reported.
They noted, as expected, the risk for kidney disease was significant for those who were diabetic. However, the risk was also significant for those who didn't have diabetes.
"Although the results for diabetic [end-stage kidney disease] were remarkable, with risks increasing sixfold and 19-fold among overweight and obese adolescents, respectively, our results also indicate a substantial association between elevated BMI and nondiabetic, end-stage renal disease," the authors wrote in the report. BMI, or body mass index, is a measurement that takes into account height and weight.
This was a study of association and can't really prove that overweight and obesity cause kidney failure, said Dr. David Katz, director of the Yale University Prevention Research Center, who was not involved with the study.
"Other factors related to lifestyle and/or environment might be the reason for both obesity and kidney failure," he said.
In this case, the findings suggest obesity is an important risk factor for end-stage kidney disease and that much of this may be accounted for by diabetes, for which obesity is a well-established risk factor, and which, in turn, is a major cause of kidney disease, Katz said.
"But, the study also indicates that obesity may lead to kidney failure even when diabetes does not develop," he added.
"I'm not sure we really need yet another reason to recognize epidemic obesity as an enormous threat to human health, and an enormous cost center. But this study suggests we have one," Katz said.
Another expert, Nancy Copperman, director of public health initiatives in the Office of Community Health at North Shore-LIJ Health System in Great Neck, N.Y., said that "obesity is not cosmetic."
"Obesity has health consequences," she added. "We need to take it seriously."
More information: For more on obesity, visit the U.S. National Library of Medicine.
Journal reference: JAMA Internal Medicine
Copyright © 2012 HealthDay. All rights reserved.
- Diabetics show alarming increase in morbid obesity Nov 23, 2009 | not rated yet | 0
- Study says overweight Americans may risk kidney damage when attempting weight loss Feb 21, 2012 | not rated yet | 0
- Reducing risk of renal failure in obese patients Apr 28, 2011 | not rated yet | 0
- Large waistlines can double the risk of death in kidney disease patients Jul 12, 2011 | not rated yet | 0
- Researchers discover that obesity hinders kidney donation May 10, 2012 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
The Durability of Bone: Long Falls
2 hours ago I am doing a paper on the physics in Valve's Portal and got interested in the "Long Fall Boots" that prevent any damage no matter how far you fall. I...
Is energy convertible to matter?
4 hours ago Can we convert energy to matter?
Rotating electron as a dipole is this right?
6 hours ago An electron as shown by the Stern Gerlach experiment behaves like a dipole (albeit only in one of two states). I have been trying to figure out how...
Dipole term in multipole expansion
10 hours ago Hi. I'm having some difficult in understanding something about the dipole term in a multipole expansion. Griffiths writes the expansion as a sum of...
Bubbles in a Pre-Boiling/Boiling pot of water
11 hours ago How is it that bubbles form on the bottom of a surface of a pot of boiling water? I think that there is probably an elementary answer to this...
Assumptions of Griffith's fracture theory
22 hours ago Any experts on Griffith's fracture theory? I am studying the subject and I am having hard time finding out if the theory is valid for all possible...
- More from Physics Forums - Classical Physics
More news stories
As many as 35 percent of Mexican young adults may have a genetic predisposition for obesity, said a University of Illinois scientist who conducted a study at the Universidad Autónoma de San Luis Potosί.
Overweight and Obesity 9 hours ago | not rated yet | 0
Overweight and obese patients are significantly more likely than their normal-weight counterparts to repeatedly switch primary care doctors, a practice that disrupts continuity of care and leads to more emergency room visits, ...
Overweight and Obesity 10 hours ago | not rated yet | 0
Children who have suffered maltreatment are 36% more likely to be obese in adulthood compared to non-maltreated children, according to a new study by King's College London. The authors estimate that the prevention or effective ...
Overweight and Obesity 20 hours ago | not rated yet | 0
(Medical Xpress)—Research by the University of Leeds has shown that very young children appear to reject story book characters who are overweight, but not those who are disabled.
Overweight and Obesity May 16, 2013 | 3 / 5 (1) | 4
(HealthDay)—Weight gain in men and women is predicted by two different genetic variations—so-called polymorphisms, according to a new study from the Netherlands.
Overweight and Obesity May 15, 2013 | 5 / 5 (1) | 0 |
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
13 hours ago | 4.2 / 5 (5) | 0 |
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
10 hours ago | 4.9 / 5 (9) | 0 |
An experimental sleeping pill from US drug company Merck is effective at helping people fall and stay asleep, according to reviewers at the US Food and Drug Administration, which could soon approve the new drug.
6 hours ago | 3 / 5 (2) | 0
Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...
7 hours ago | 5 / 5 (3) | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
12 hours ago | 4.5 / 5 (6) | 0 |
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
8 hours ago | 5 / 5 (1) | 0 |