Prognosis after cystectomy not affected by smoking

October 15, 2012
Prognosis after cystectomy not affected by smoking
Despite the link between cigarette smoking and the development of bladder cancer, the prognosis of people with bladder cancer after undergoing a cystectomy is not affected by cigarette smoking, according to research published online Oct. 8 in Urology.

(HealthDay)—Despite the link between cigarette smoking and the development of bladder cancer, the prognosis of people with bladder cancer after undergoing a cystectomy is not affected by cigarette smoking, according to research published online Oct. 8 in Urology.

In an effort to determine the effect of cigarette smoking on recurrence-free, cancer-specific, and overall survival, Chunwoo Lee, M.D., of the Asan Medical Center in Seoul, , and colleagues conducted a study involving 602 patients who had undergone radical cystectomy for bladder cancer.

The researchers found that, overall, 340 people had smoked and 159 were current smokers. For smokers and nonsmokers, the five-year recurrence-free survival rates were 62.1 and 56.8 percent, respectively. The five-year cancer-specific were 67.3 and 63.9 percent for smokers and nonsmokers, respectively. Finally, the five-year overall survival rate was 63.0 percent for smokers and 58.8 percent for nonsmokers. None of these between-group differences were statistically significant.

"The results of the present study suggest that smoking history is not a significant for the survival of operable patients with after radical cystectomy," the authors write. "However, it was not possible to ascertain whether smoking and the ensuing effects precluded some patients from undergoing radical cystectomy to begin with."

Explore further: Patients unaware of link between smoking and bladder cancer

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Patients unaware of link between smoking and bladder cancer

July 8, 2008

Even though cigarette smoking accounts for up to half of all bladder cancer cases, few people are aware of the connection – including more than three-quarters of patients who have bladder cancer, according to a new study ...

Bladder cancer risks increase over time for smokers

November 16, 2009

Risk of bladder cancer for smokers has increased since the mid-1990s, with a risk progressively increasing to a level five times higher among current smokers in New Hampshire than that among nonsmokers in 2001-2004, according ...

Recommended for you

Oxygen can impair cancer immunotherapy in mice

August 25, 2016

Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers. This mechanism involves oxygen inhibition of the anticancer ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.