A simple blood test could be used to detect breast cancer
A simple blood test could one day be a more accurate way to test for the early signs of breast cancer than using mammograms to spot a lump say researchers today, as Breast Cancer Awareness Month gets underway.
This pioneering new clinical study – funded by Cancer Research UK in collaboration with the University of Leicester and Imperial College London – is about to start in the UK's largest breast screening clinic at Charing Cross Hospital, London.
Researchers will take blood samples from women attending the breast screening clinic and compare the DNA in the blood of women who are diagnosed with breast cancer with those that do not have cancer to see what DNA markers are consistent.
Dr Jacqui Shaw, principal investigator from the University of Leicester, said: "This exciting research means we could one day have a blood test that detects the very early signs of cancer meaning women could have an annual blood test rather than breast screening. This would remove any worry and anxiety for women who are called for further investigations after a mammogram only to find they don't have cancer.
"As things stand we aren't able to monitor breast cancer patients after they've had surgery and treatment - which is like treating diabetes but not measuring blood sugar levels. The new blood test could change that."
Professor Charles Coombes, co-investigator and Cancer Research UK's breast cancer expert from Imperial College, said: "This type of translational science is extremely promising and the international scientific community is collaborating on its development. When a woman has breast cancer we can tell by the DNA in their blood. But what we're trying to find out in our study is how early the signs of breast cancer show up in a blood test. So by looking at blood samples of women who have breast cancer diagnosed through screening we can see if the cancer is already showing in their blood.
"Our research team is only looking at breast cancer but there are a number of other projects that are looking at using a blood test to detect other cancers such as bowel and lung."
Kate Law, director of clinical research at Cancer Research UK, said: "We really do hope that in the not too distant future a simple blood test for breast cancer, which could not only detect cancer but help with treatment options, will become standard practice on the NHS.
"Cancer Research UK has invested over a million pounds into this project as this fascinating area of science could prove to be a huge step forward in the way certain types of cancer are diagnosed and treated."
Provided by University of Leicester
- PSA test for men could get a second life for breast cancer in women Jul 13, 2011 | not rated yet | 0
- Report: New test for breast cancer Aug 03, 2006 | not rated yet | 0
- Breast cancer type linked to paternal cancer Nov 28, 2011 | not rated yet | 0
- New technique to study the genetics of breast cancer Nov 11, 2008 | not rated yet | 0
- No need for gene screens in breast cancer families Jul 23, 2008 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
How can there be a term called "intestinal metaplasia" of stomach
6 hours ago Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
- More from Physics Forums - Medical Sciences
More news stories
The surgical management of non-small cell lung cancer (NSCLC) in U.S. hospitals varies widely depending on the race of the patient, according to a new study.
Cancer 3 hours ago | not rated yet | 0
Treatment with an Alpha-1 proteinase inhibitor (A1-PI), a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients ...
Cancer 3 hours ago | not rated yet | 0
Scientists from Nanyang Technological University (NTU) and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumour cells.
Cancer 4 hours ago | 5 / 5 (1) | 0
An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induce ...
Cancer 4 hours ago | not rated yet | 0
(Medical Xpress)—Scientists at the School of Medicine have shown that their previously identified therapeutic approach to fight cancer via immune cells called macrophages also prompts the disease-fighting killer T cells ...
Cancer 6 hours ago | not rated yet | 0 |
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
4 minutes ago | not rated yet | 0 |
You're standing near an airport luggage carousel and your bag emerges on the conveyor belt, prompting you to spring into action. How does your brain make the shift from passively waiting to taking action when ...
43 minutes ago | not rated yet | 0 |
Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older ...
1 hour ago | 5 / 5 (1) | 0 |
Children who are exposed to secondhand smoke in early childhood are more likely to grow up to physically aggressive and antisocial, regardless of whether they were exposed during pregnancy or their parents have a history ...
27 minutes ago | 1 / 5 (1) | 0
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
2 hours ago | 3.5 / 5 (2) | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
2 hours ago | 4.5 / 5 (2) | 0 |