Study assesses bidirectional link for diabetes, depression

November 19, 2012
Study assesses bidirectional link for diabetes, depression
There is a bidirectional relationship between type 2 diabetes and depression, with a stronger correlation for depression predicting diabetes onset, according to research published online Nov. 12 in Diabetes Care.

(HealthDay)—There is a bidirectional relationship between type 2 diabetes and depression, with a stronger correlation for depression predicting diabetes onset, according to research published online Nov. 12 in Diabetes Care.

Pei-Chun Chen, Ph.D., of the National Taiwan University College of Public Health in Taipei, and colleagues conducted two cohort studies using the same database source to address the strength of the for a bidirectional relationship between depression and . To analyze diabetes predicting depression onset, 16,957 patients with type 2 diabetes and an equal number of age- and sex-matched individuals without diabetes were assessed. To analyze depression predicting diabetes onset, 5,847 patients with depression and an equal number of without depression were evaluated. Participants were followed from 2000 to 2006.

In the first cohort analysis, the researchers found that the incidence density for depression was 7.03 per 1,000 person-years for those with diabetes and 5.04 per 1,000 person-years for those without diabetes, representing an adjusted hazard ratio of 1.43. In the second cohort, the incidence density for diabetes was 27.59 and 9.22 per 1,000 person-years in those with and without depression, respectively. The adjusted hazard ratio for incident diabetes was 2.02 in association with baseline depression.

"The two cohort studies provided evidence for the bidirectional relationship between diabetes and depression, with a stronger association noted for the depression predicting onset of diabetes," the authors write.

Explore further: Combo of diabetes, depression increases post-MI mortality

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Combo of diabetes, depression increases post-MI mortality

February 27, 2012

(HealthDay) -- Having both diabetes and depression significantly increases the risk of dying in the years following a heart attack, beyond the increased risk from either condition alone, according to a study published in ...

In Taiwan, diabetes linked to increased Parkinson's risk

April 2, 2012

(HealthDay) -- Individuals with diabetes in Taiwan have a significantly increased risk of Parkinson's disease (PD), which is robust across most age and gender stratifications, according to a study published online March 19 ...

Depression found to increase risk of death in diabetes

June 1, 2012

(HealthDay) -- For patients with type 2 diabetes, depression is associated with an increased risk of all-cause mortality, regardless of previous cardiovascular disease, according to a study published online May 22 in Diabetes ...

Recommended for you

Research shows nerve growth protein controls blood sugar

November 14, 2016

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

Researchers discover new regulator in glucose metabolism

November 9, 2016

A key genetic switch in the liver regulates glucose metabolism and insulin action in other organs of the body. Researchers of Helmholtz Zentrum München, in collaboration with colleagues of the Heidelberg University Hospital, ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.