Dengue vaccine to be tested in India

French health care giant Sanofi Pasteur will soon test a vaccine against dengue fever in India amid concerns about the increasingly global spread of the disease, reports said Monday.

The vaccine will be tried on about 120 adults followed by trials on children before it can be made available internationally as soon as 2015, the Times of India newspaper said.

"Sites for the vaccine's final trials will stretch from Thailand to India as this vaccine has to work on populations across countries. We will test it in India soon," Sanofi's CEO Christopher Viehbacher was quoted as saying.

Dengue causes a flu-like illness for most victims but one of its strains can cause life-threatening internal bleeding.

There is no licensed vaccine to protect against dengue. Efforts to develop one have been complicated by the fact that there are four different strains, all of which may circulate in an outbreak zone.

Dengue also seems to be exclusive to humans, which means it is impossible to test vaccines on first.

Jean Lang, head of the vaccine's research and development programme, said Sanofi had been asked to conduct "phase two safety trials" in India by the national drug controller.

"It will help us get a licence to market the in India faster if it has been tested on the Indian population and is found safe and effective," Lang told the paper.

According to the UN's , between 50 and 100 million dengue infections occur each year in more than 100 countries. In 1970 the disease was endemic in just nine countries.

India, with a teeming population of 1.2 billion, has become a major focal point for the mosquito-borne viral infection.

Between 2007 and this month, the country has had 32,263 dengue cases with 188 deaths, according to the National Control Programme. Experts say the real numbers are much higher.

add to favorites email to friend print save as pdf

Related Stories

Dengue vaccine could be ready by 2015: Sanofi

Jun 10, 2011

French drugs group Sanofi said Friday that its vaccine against dengue, a mosquito-borne infection that kills thousands of people around the world each year, could be launched in about four years.

Progress reported with candidate dengue vaccine

Jul 25, 2012

Trials in Thailand with a candidate vaccine for dengue, a potentially fatal mosquito-borne disease, have shown it to protect against three of the four virus strains, its French maker said Wednesday.

Thailand developing dengue vaccine: researcher

Feb 22, 2011

Researchers in Thailand say they have developed a prototype vaccine against dengue fever and will conduct further tests with the aim of bringing it to market within a decade.

Scientists make dengue vaccine breakthrough

Sep 10, 2012

Dengue is one of the most widespread mosquito-borne viral diseases in the world, with WHO estimating that around half of the world's population are currently at risk. While infection usually causes flu-like symptoms, it can ...

Concerns over cost of dengue vaccine lessened with new study

Jun 28, 2012

Research funded by the Dengue Vaccine Initiative (DVI) involving an economic analysis of producing a tetravalent dengue vaccine shows that the cost could be as low as $0.20 per dose with an annual production level of 60 million ...

Recommended for you

WHO: Ebola moving faster than control efforts

7 minutes ago

An Ebola outbreak that has killed more than 700 people in West Africa is moving faster than the efforts to control the disease, the head of the World Health Organization warned as presidents from the affected ...

Quick blood test for malaria

42 minutes ago

Siemens is working on a procedure that would allow blood to be routinely tested for malaria. Physicians normally diagnose the tropical disease by using a microscope to search for parasites in blood samples. ...

User comments