Endovascular, open aneurysm repair long-term survival akin

Endovascular, open aneurysm repair long-term survival akin
For repair of abdominal aortic aneurysms, endovascular repair and open repair result in similar long-term survival, according to a study published in the Nov. 22 issue of the New England Journal of Medicine.

(HealthDay)—For repair of abdominal aortic aneurysms, endovascular repair and open repair result in similar long-term survival, according to a study published in the Nov. 22 issue of the New England Journal of Medicine.

Frank A. Lederle, M.D., from the Veterans Affairs Medical Centers in Minneapolis, and colleagues randomly assigned 881 patients (49 years or older) with asymptomatic to either endovascular repair (444 patients) or open repair (437 patients) and followed them for a mean of 5.2 years.

The researchers found that 146 deaths occurred in each group. There was a significant reduction in perioperative with endovascular repair at two years (hazard ratio [HR], 0.63; P = 0.04) and at three years (HR, 0.72; P = 0.05), but not thereafter. In the endovascular-repair group there were 10 aneurysm-related deaths, compared to 16 in the open-repair group (2.3 versus 3.7 percent; P = 0.22). In the endovascular-repair group there were six confirmed ruptures versus none in the open-repair group (P = 0.03). In the endovascular-repair group, survival was significantly increased among patients under 70 years of age, while for patients age 70 years or older, survival tended to be better for those in the open-repair group.

"Our results suggest that endovascular repair continues to improve and is now an acceptable alternative to open repair even when judged in terms of long-term survival," the authors write.

More information: Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Study: Removing clot helps limit stroke disability

Dec 17, 2014

For the first time in several decades, a new treatment has been shown to limit the damage from a common type of stroke. Researchers in the Netherlands found that mechanically removing a clot in addition to using a clot-busting ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.