Home field advantage: Intravaginal immunization may help protect against infection

November 12, 2012 in Immunology

Sexually-transmitted diseases (STDs) enter the body through the mucosal epithelial cells and the ability to direct pathogen-clearing T-cells to points of infection may be the critical element in developing successful vaccines against these infections.

In a study published in the Journal of Clinical Investigation, researchers led by John Schiller at the investigated the immune response to intravaginal immunization in mice infected with a form of the HPV virus carrying a model antigen.

They found that intravaginal immunization significantly increased the number of immune cells present in the vaginal mucosa compared with a general immune system booster.

These results indicate that site-specific vaccination enhances the local and may be useful in developing STD vaccines.

More information: Intravaginal immunization with HPV vectors induces tissue-resident CD8+ T cells, Journal of Clinical Investigation, 2012.

Journal reference: Journal of Clinical Investigation search and more info website

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saraet
Nov 13, 2012

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DateHSV...com is a place for you to find information, friendship, hope, support, and romance. HPV information herpes dating herpes personals HSV HIV/AIDS STD medical treatments and information. No matter what kind of STDs you have, or just curious to see what's on here can register profile and conduct profile search for free.
saraet
Nov 13, 2012

Rank: not rated yet
DateHSV...com is a place for you to find information, friendship, hope, support, and romance. HPV information herpes dating herpes personals HSV HIV/AIDS STD medical treatments and information. No matter what kind of STDs you have, or just curious to see what's on here can register profile and conduct profile search for free.
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national cancer institute, immune system response, journal of clinical investigation, immune system booster, hpv virus, immune cells, immune response, vaccine
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