QoL up for live liver donors versus general population

QoL up for live liver donors versus general population
Living liver donors from Japan have higher health-related quality of life than the Japanese norm population, according to a study published in the November issue of Liver Transplantation.

(HealthDay)—Living liver donors from Japan have higher health-related quality of life (HRQOL) than the Japanese norm population, according to a study published in the November issue of Liver Transplantation.

Yasutsugu Takada, M.D., Ph.D., from Ehime University in Toon, Japan, and colleagues studied the long-term effects of living on the HRQOL of 578 donors using the Short Form-36 .

The researchers found that, across all time periods, norm-based HRQOL scores for donors were better than the scores for Japanese norms. Age, the number of months until recovery to the preoperative , hospital visits due to donation-related symptoms, rest from work related to donation in the past month, and the existence of two or more comorbidities correlated significantly with reduced HRQOL scores for all donors. Recipient mortality and were not predictors of poor HRQOL.

"HRQOL was better for both right lobe donors and left lobe donors versus the Japanese norm population in the long term (mean post-donation period = 6.8 years). However, the prolongation of symptoms or sequelae related to donation lowered mental health or social functioning. The emergence of comorbidities after donation also significantly affected HRQOL in the long term," the authors write. "Careful follow-up and sustained counseling are required for donors with risk factors for lower HRQOL."

More information: Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Living donors fare well following liver transplantation

Nov 01, 2012

Researchers in Japan report that health-related quality of life (HRQOL) for donors following living donor liver transplantation (LDLT) was better than the general Japanese population (the norm). This study—one of the largest ...

Study shows lifetime effects of pediatric liver transplants

Mar 26, 2008

Parents of pediatric liver transplant recipients report lower health-related quality of life for their children two years after the surgery, compared to reports from the parents of healthy children. However, reports of family ...

Recommended for you

Face transplants change lives, identity

11 hours ago

Patients are prepared to take significant risks in order to be considered for a face transplant, says Dr David Koppel, director of the largest craniofacial unit in the UK and Honorary Clinical Associate Professor ...

British Lords hold ten-hour debate on assisted dying

Jul 19, 2014

Members of Britain's unelected House of Lords spent almost ten hours on Friday discussing whether to legalise assisted dying, in an often emotional debate putting the question back on the agenda, if not on the statute books.

AbbVie, Shire agree on $55B combination

Jul 18, 2014

The drugmaker AbbVie has reached a deal worth roughly $55 billion to combine with British counterpart Shire and become the latest U.S. company to seek an overseas haven from tax rates back home.

User comments