Research supports role of BMI in incident asthma in children

November 20, 2012
Research supports role of BMI in incident asthma in children
Overweight and obese children have a significantly increased risk of incident asthma, with evidence of a dose-response effect of elevated body mass index, according to a meta-analysis published online Nov. 12 in Obesity Reviews.

(HealthDay)—Overweight and obese children have a significantly increased risk of incident asthma, with evidence of a dose-response effect of elevated body mass index (BMI), according to a meta-analysis published online Nov. 12 in Obesity Reviews.

Y.C. Chen, from the National Taiwan University in Taipei, and colleagues reviewed the literature and conducted a meta-analysis using a prospective cohort of pediatric studies that analyzed age- and sex-specific BMI (as a measure of childhood overweight) and the primary outcome of incident asthma.

Based on data from six studies meeting the inclusion criteria, the researchers found that, compared with non-, overweight children had increased risks of incident asthma (relative risk [RR], 1.19). When comparing obese versus non-, the association was further elevated (RR, 2.02). There was a significant dose-responsiveness of elevated BMI on asthma incidence (P for trend, 0.004). In addition, there was a gender difference noted, with obese boys exhibiting a significantly larger effect than obese girls (RR, boys: 2.47; girls: 1.25), also with a significant dose-dependent effect.

"Our findings support the impact of on incident asthma, and provide information to compel obese children to lose weight," the authors write. "Policy makers for children's health and parents should pay more attention on preventing obesity-associated risk and environments."

Explore further: 'Belly fat' linked to development of asthma

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Recommended for you

A metabolic master switch underlying human obesity

August 19, 2015

Obesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone, and contributes to potentially ...

Scientists probe obesity's ties to breast cancer risk

August 20, 2015

Obesity is a well-known risk factor for breast cancer, but researchers haven't figured out what connects the two. A new study suggests the link may be due to a change in breast tissue structure, which might promote breast ...

Can a new drug brown the fat and trim the obese person?

May 28, 2015

New research has found that a variant of a drug used to treat pulmonary arterial hypertension prompts weight loss in obese mice. Among mice fed a high-fat diet, those who did not get the medication became obese while medicated ...

Changing stem cell structure may help fight obesity

February 17, 2015

The research, conducted at Queen Mary University of London (QMUL), found that a slight regulation in the length of primary cilia, small hair-like projections found on most cells, prevented the production of fat cells from ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.