AES: Brain's stress response differs among epilepsy patients

AES: brain's stress response differs among epilepsy patients
There is a significant difference in the brain's response to stress among patients with epilepsy who believe stress is an important factor in seizure control compared to those who do not, according to a study presented at the annual meeting of the American Epilepsy Society, held from Nov. 30 to Dec. 4 in San Diego.

(HealthDay)—There is a significant difference in the brain's response to stress among patients with epilepsy who believe stress is an important factor in seizure control compared to those who do not, according to a study presented at the annual meeting of the American Epilepsy Society, held from Nov. 30 to Dec. 4 in San Diego.

Using functional , Jane B. Allendorfer, Ph.D., from the University of Alabama at Birmingham, and colleagues assessed the neural response to psychosocial stress in 23 patients with left . Participants included 16 patients who believed that stress impacts their (+S) and seven who did not (−S). The Montreal Imaging Stress Task was used as the stress paradigm, whereby participants performed a simple (control) and difficult (stress) task, with positive and negative feedback provided in the simple and difficult tasks, respectively.

The researchers found that, in the +S group, there was increased activation bilaterally in the superior temporal gyrus (STG) in response to the difficult versus simple math problems. In response to negative versus positive feedback, in the +S group, there was increased activation in the left insula and bilaterally in the STG, Brodmann area 39, and posterior cingulate. Increased activation was not seen in stressful conditions in the −S group.

"We also hypothesize that the difference in may be related to why some epilepsy patients have seizures more frequently than do other patients," Allendorfer said in a statement.

More information: Abstract
More Information

Related Stories

Study supports link between stress, epileptic seizures

date Dec 04, 2012

(HealthDay)—Scientists have long thought that stress plays a role in epileptic seizures, and new evidence suggests that epilepsy patients who believe this is the case experience a different brain response ...

Surgery a safe, effective option for many epilepsy patients

date Mar 23, 2012

Treatment for epilepsy typically focuses on medication, with some patients spending 20 years or more on a variety of drugs in search of effective management of the condition. But a UC Health neurologist says that for many ...

Recommended for you

Making waves with groundbreaking brain research

date 23 hours ago

New research by Jason Gallivan and Randy Flanagan suggests that when deciding which of several possible actions to perform, the human brain plans multiple actions simultaneously prior to selecting one of ...

Long-term memories are maintained by prion-like proteins

date Jul 02, 2015

Research from Eric Kandel's lab at Columbia University Medical Center (CUMC) has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time. And paradoxically, ...

Water to understand the brain

date Jul 02, 2015

To observe the brain in action, scientists and physicians use imaging techniques, among which functional magnetic resonance imaging (fMRI) is the best known. These techniques are not based on direct observations ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.