Cartenoids found to reduce hip fracture risk in lean men

December 16, 2012

Speaking at the IOF Regionals Asia-Pacific Osteoporosis Meeting, researchers from the National University of Singapore and the Singapore Ministry of Health, announced a study which links carotenoids to decreased hip fracture risk in elderly, lean Chinese men. Elderly who are lean (BMI <20 kg/m2) are at higher risk of hip fracture compared to those with higher BMI.

In the study, the researchers examined the association between dietary antioxidant carotenoids and hip fracture risk across a range of in elderly Chinese men and women using data from the Singapore Chinese Health Study. This population-based, cohort prospective study recruited 63,257 men and women aged 45 years between 1993. In this group, a total of 1,630 incident hip fractures up to December 2010 were identified via record linkage with the nationwide hospital discharge database.

Importantly, the study found that low BMI is a stronger risk factor for hip fracture risk among elderly men compared to women.

Also, in men, hip fracture risk decreased with increasing intakes of total vegetables and of total carotenoids, particularly β-carotene. The protective effect was higher in lean men than in men with higher BMI. In contrast, the intake of vegetables or carotenoids had no association with hip fracture risk in women, regardless of levels of BMI.

Cartenoids, which are found many fruits and vegetables (and especially in yellow and orange pigmented vegetables) are converted to vitamin A in the body. The researchers conclude that clinical trials are needed to demonstrate the efficacy of carotenoid supplementation on reduction of hip fracture risk in . The findings may have important public health implications on hip fracture prevention, particularly among .

Abstracts from the IOF Regionals 3rd Asia-Pacific Meeting have been published in the scientific journal Osteoporosis International.

Explore further: Nearly two-thirds of American osteoporotic hip fractures are seen in the extreme elderly

Related Stories

Changing trends in hip fracture incidence around the world

April 12, 2011

Osteoporosis constitutes a major public health problem through its association with age-related fractures, most notably those of the hip. As life expectancy rises around the world, along with the number of elderly people ...

Recommended for you

Zika virus infection alters human and viral RNA

October 20, 2016

Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications—chemical tags known as ...

Food-poisoning bacteria may be behind Crohn's disease

October 19, 2016

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn's disease later in life, according to a new study led by researchers at McMaster University.

Neurodevelopmental model of Zika may provide rapid answers

October 19, 2016

A newly published study from researchers working in collaboration with the Regenerative Bioscience Center at the University of Georgia demonstrates fetal death and brain damage in early chick embryos similar to microcephaly—a ...

Scientists uncover new facets of Zika-related birth defects

October 17, 2016

In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute (TSRI) have elucidated how the virus attacks the brains of newborns, ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.