Low insulin secretion tied to depressive symptoms in women
Middle-aged women with insulin secretion levels in the lowest quintile appear to have more than twice the risk of developing new-onset depressive symptoms compared with those with higher insulin secretion levels, according to research published online Dec. 10 in Diabetes Care.
(HealthDay)—Middle-aged women with insulin secretion levels in the lowest quintile appear to have more than twice the risk of developing new-onset depressive symptoms compared with those with higher insulin secretion levels, according to research published online Dec. 10 in Diabetes Care.
Tasnime N. Akbaraly, Ph.D., of University College London, and colleagues conducted a prospective cohort study involving 3,145 adults (23.5 percent women) with an average age of 60.6 years to examine the correlation between glycemia, insulin resistance, and insulin secretion with subsequent new-onset depressive symptoms.
The researchers found that depressive symptoms developed in 142 men and 84 women over the five-year follow-up. The odds of developing new onset depressive symptoms were 2.18-fold higher for women in the lowest quintile of insulin secretion, defined as the homeostasis model assessment of β-cell insulin secretion ≤55.3 percent, compared with those with higher insulin secretion. Inflammatory markers, cortisol secretion, or menopausal status and hormone replacement therapy did not explain the association. There was no correlation between fasting insulin measures and new-onset depressive symptoms for men, and in neither sex were fasting glucose measures associated with new-onset symptoms.
"Low insulin secretion appears to be a risk factor for new onset depressive symptoms in middle-aged women, although further work is required to confirm this finding," the authors write.
More information: Abstract
Full Text (subscription or payment may be required)
Journal reference:
Diabetes Care
Copyright © 2012 HealthDay. All rights reserved.
-
Absolute incretin effect reduced in type 2 diabetes
Jun 25, 2012 |
not rated yet |
0
-
Sleep apnea tied to insulin resistance in young, lean men
Aug 29, 2012 |
not rated yet |
0
-
How does insulin influence resistin?
Jan 16, 2008 |
not rated yet |
0
-
A body temperature sensor, TRPM2, promotes insulin secretion
Jan 04, 2011 |
not rated yet |
0
-
Hyperinsulinemia in early adulthood tied to later HTN
Jun 28, 2012 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Image of a Convex Lens Cut in Half Horizontally
2 hours ago
-
Ray tracing throught optical system of thick lenses
2 hours ago
-
Faraday's law on circular wire
3 hours ago
-
Specific Exergy vs Specific Flow Exergy
5 hours ago
-
The Durability of Bone: Long Falls
13 hours ago
-
Is energy convertible to matter?
15 hours ago
- More from Physics Forums - Classical Physics
More news stories
Study shows that women who smoke during pregnancy increase the risk of both obesity and gestational diabetes in their da
Women who smoke during pregnancy increase the risk of both obesity and gestational diabetes, in their daughters, concludes research published in Diabetologia, the journal of the European Association for the Study of Diabet ...
Diabetes
May 20, 2013 |
not rated yet |
0
Rise in type 2 diabetes amongst young
The number of young people diagnosed with type 2 diabetes has seen the sharpest rise over the last twenty years compared to a background of a general increase across the board, new University research has ...
Diabetes
May 20, 2013 |
not rated yet |
0
Research uncovers a potential role of two proteins in diabetes
(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.
Diabetes
May 20, 2013 |
5 / 5 (2) |
0
|
Exercise prevents fructose-induced hypertriglyceridemia
(HealthDay)—Moderate aerobic exercise prevents fructose-induced hypertriglyceridemia in healthy males, according to a study published online May 14 in Diabetes.
Diabetes
May 17, 2013 |
5 / 5 (1) |
0
|
DNA variant affects diabetes risk and treatment response
A DNA variant near a digestive enzyme does not only affect risk of developing diabetes but also affects the response to treatment, an international consortium of researchers including the University of Dundee has found.
Diabetes
May 17, 2013 |
not rated yet |
0
|
Study finds new pneumococcal vaccine appears to be as safe as previously used vaccine
The new 13-valent pneumococcal conjugate vaccine (PCV13) appears to be as safe as the previous version used prior to 2010, the 7-valent pneumococcal conjugate vaccine (PCV7), according to a Kaiser Permanente study published ...
Addiction to unhealthy foods could help explain the global obesity epidemic
Research presented today shows that high-fructose corn syrup can cause behavioural reactions in rats similar to those produced by drugs of abuse such as cocaine. These results, presented by addiction expert Francesco Leri, ...
Study says empathy plays a key role in moral judgments
Is it permissible to harm one to save many? Those who tend to say "yes" when faced with this classic dilemma are likely to be deficient in a specific kind of empathy, according to a report published in the scientific journal ...
A molecular explanation for age-related fertility decline in women
(Medical Xpress)—Scientists supported by the National Institutes of Health have a new theory as to why a woman's fertility declines after her mid-30s. They also suggest an approach that might help slow ...
If you can remember it, you can remember it wrong
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
Phthalates: Study links chemicals widely found in plastics, processed food to elevated blood pressure in children, teens
Plastic additives known as phthalates (pronounced THAL-ates) are odorless, colorless and just about everywhere: They turn up in flooring, plastic cups, beach balls, plastic wrap, intravenous tubing and—according to the ...