Liver transplant outcomes no worse with echo abnormalities

Liver transplant outcomes no worse with echo abnormalities
Intracardiac shunts, diagnosed using an echocardiogram, or mild or moderate pulmonary hypertension, do not affect short- or long-term mortality in liver transplant candidates, according to research published online in the Dec. 15 issue of The American Journal of Cardiology.

(HealthDay)—Intracardiac shunts (ICSs), diagnosed using an echocardiogram, or mild or moderate pulmonary hypertension (PH), do not affect short- or long-term mortality in liver transplant candidates, according to research published online in the Dec. 15 issue of The American Journal of Cardiology.

Matthew E. Harinstein, M.D., of the University of Pittsburgh Medical Center, and colleagues conducted a involving 502 consecutive patients (318 men) with end-stage liver disease who had echocardiography prior to . Contrast echocardiography was used to diagnose ICSs, and PH was defined as pulmonary artery systolic pressure >40 mm Hg.

The researchers found that more than 50 percent of the study population had at least two : ICSs were found in 16 percent, PH in 25 percent, and intrapulmonary shunts in 41 percent of liver transplant candidates. Short-(30-day) and long-term (mean, 41 months) mortality was not associated with ICSs or PH. Furthermore, no strokes occurred in those with ICSs.

"In conclusion, structural differences exist between various end-stage liver disease diagnoses. ICSs diagnosed by echocardiography are not associated with an increased risk of perioperative stroke or increased mortality. A diagnosis of mild or moderate PH on baseline echocardiogram is not associated with worse outcomes and requires further assessment," the authors write. "Based on these findings, patients should not be excluded from consideration for liver transplantation based solely on the presence of an ICS or PH."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Senegal monitors contacts of 1st Ebola patient

1 hour ago

Senegalese authorities on Monday were monitoring everyone who was in contact with a student infected with Ebola who crossed into the country, and who has lost three family members to the disease.

Cerebral palsy may be hereditary

7 hours ago

Cerebral palsy is a neurological developmental disorder which follows an injury to the immature brain before, during or after birth. The resulting condition affects the child's ability to move and in some ...

19 new dengue cases in Japan, linked to Tokyo park

13 hours ago

Japan is urging local authorities to be on the lookout for further outbreaks of dengue fever, after confirming another 19 cases that were contracted at a popular local park in downtown Tokyo.

User comments