NIH scientists reflect on gains in emerging infectious disease awareness, research and response
In a new essay, National Institute of Allergy and Infectious Diseases director Anthony S. Fauci, M.D., and David Morens, M.D., reflect on what has been learned about emerging infectious diseases (EIDs) in the two decades since a major report from the U.S. Institute of Medicine rekindled interest in this important topic.
Heightened awareness of EIDs is itself a countermeasure against disease, note the authors. The emergence of new diseases can now be monitored in real time online through Internet resources such as ProMED. In 2012 alone, such resources kept the scientific community and the public informed about the emergence in the Middle East of a novel disease-causing coronavirus; occurrences of illness at Yosemite National Park caused by a hantavirus; and the emergence in U.S. farm communities of a variant influenza virus (H3N2v) that spread from swine to people. The authors point to advances that have improved the diagnosis, treatment and prevention of EIDs. Rapid sequencing of whole genomes, for example, allows for swift identification of new disease agents. The complex interactions between disease-causing microbes and human hosts are being revealed through approaches that describe entire biological systems holistically (systems biology). The data from such studies can be used to inform the development of drugs or vaccines. Recent appreciation of the sometimes beneficial role of communities of microorganisms dwelling in the gut, mouth, skin and other niches has reshaped the standard notion of infectious diseases as a simple contest between virulent invading pathogens and the human immune system.
The scientists emphasize the need for sustained commitment to developing countermeasures for specific diseases and to basic research that will lead to a greater understanding of infectious diseases and human susceptibility.
More information: DM Morens and AS Fauci. Emerging infectious diseases in 2012: 20 years after the Institute of Medicine report. mBio DOI: 10.1128/mBio.00494-12 (2012) (http://mbio.asm.org/content/3/6/e00494-12).
Journal reference: mBio
- NIAID scientists consider 200 years of infectious diseases Feb 02, 2012 | not rated yet | 0
- Report focuses on sustainability of infectious disease surveillance Jul 17, 2012 | not rated yet | 0
- DNA of good bacteria drives intestinal response to infection Oct 02, 2008 | not rated yet | 0
- Researcher explores role of human behavior in infectious disease emergence Apr 29, 2010 | not rated yet | 0
- Ыcientists explore 1510 influenza pandemic and lessons learned Nov 12, 2010 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
(AP)—Government health officials are investigating several health problems reported with potentially contaminated medications made by a Tennessee specialty pharmacy.
Diseases, Conditions, Syndromes 19 hours ago | not rated yet | 0
(HealthDay)—Comorbid conditions often accompany alopecia areata, according to a study published online May 22 in JAMA Dermatology.
Diseases, Conditions, Syndromes 20 hours ago | not rated yet | 0
(HealthDay)—As a world-class golfer, Stacy Lewis' accomplishments are remarkable. But it was a physical challenge in her childhood that defined her ascent to the top of her sport.
Diseases, Conditions, Syndromes 21 hours ago | not rated yet | 0
Saudi Arabia said Friday it would send samples taken from animals possibly infected with a deadly SARS-like virus to the United States for testing in a bid to find the source of disease.
Diseases, Conditions, Syndromes May 24, 2013 | not rated yet | 0
The World Health Organization voiced deep concern Thursday over the SARS-like virus that has killed 22 people in less than a year, saying it might potentially spread more widely between humans.
Diseases, Conditions, Syndromes May 24, 2013 | 5 / 5 (1) | 0
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
3 hours ago | not rated yet | 4
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
22 hours ago | 3.7 / 5 (3) | 3 |
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
3 hours ago | not rated yet | 1
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
19 hours ago | 3 / 5 (2) | 0 |
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
22 hours ago | 5 / 5 (5) | 0 |
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
3 hours ago | not rated yet | 0