Changing advice: Egg-allergic patients should get flu vaccine without delay
New recommendations from a task force of allergy experts advise people with an egg allergy to get a flu vaccine, and not to delay with allergy testing before the vaccine. Patients had previously been cautioned about vaccination because of concerns about adverse reactions to egg protein in the vaccine.
"The new approach to patients with an egg allergy is that we now will administer the injectable, inactivated influenza vaccine without any prior testing," said Mark Boguniewicz, MD, pediatric allergist-immunologist at National Jewish Health in Denver. "Any risk of a reaction to the small amounts of egg protein in vaccines is outweighed by risks posed by the flu."
The new practice parameters, published in July 2012, were developed through a joint effort of the American Academy of Allergy, Asthma & Immunology, the American College of Allergy, Asthma & Immunology, and the Joint Council of Allergy, Asthma & Immunology.
Boguniewicz also emphasized that it is not too late to get a vaccine this season. The current 2012-2013 flu season has gotten off to a strong start, with serious cases and some deaths reported around the country including in Colorado.
While the average flu season generally begins in December, it does not peak until February and continues into March. Each season has its own profile, and physicians at National Jewish Health are generally offering the vaccine to all their patients who have not yet gotten one, and will do so until infectious disease experts advise them not to.
"I give vaccinations to egg allergic patients almost every day," said Boguniewicz. "Our experience at National Jewish Health is that flu vaccines can be safely administered even to patients with a history of systemic, anaphylactic reactions."
Flu vaccines are manufactured by first growing the influenza virus in chicken eggs or cell cultures made from them. As a result, there is some egg protein in all vaccines, which has raised concerns about adverse reactions in patients with egg allergy.
Previous recommendations from this task force, published in 2009, recommended a more involved and cautionary procedure, involving allergy skin tests and divided doses. The new guidelines offer a more streamlined procedure, intended to protect more egg-allergic patients from the flu. Skin testing is no longer recommended prior to vaccination, and neither is a dose divided into two smaller fractions.
Patients with a history of allergic reactions to eggs are advised to get an injectable inactivated virus vaccine, rather than the nasal vaccine containing a weakened, but live virus. Patients should get the vaccine only at facilities experienced and equipped to recognize and treat an anaphylactic reactions. Those patients are also advised to remain at the facility for 30 minutes to be observed for possible allergic reactions.
"We have found flu vaccines to be safe in the overwhelming majority of our egg-allergic patients," said Dr. Boguniewicz. There does, however, remain a small chance of a severe reaction. "I tell my patients that since it is unpredictable, let's do it in a safe environment."
Provided by National Jewish Health
- Egg allergy: Not a reason to avoid flu vaccine after all Oct 18, 2010 | not rated yet | 0
- Researchers evaluating food allergy treatment Apr 17, 2008 | not rated yet | 0
- Study suggests potential hurdle to universal flu vaccine development may be overcome Aug 15, 2012 | not rated yet | 0
- Six bad reactions to swine flu vaccine in Canada: official (Update) Nov 24, 2009 | not rated yet | 0
- No Excuses: Flu vaccination myths addressed Oct 12, 2012 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
5 hours ago Alright, so in Pathfinder (like Dungeons and Dragons) there's a spell that allows you to lift/move stuff within 25 ft with 5 pounds of force. A...
8 hours ago So energy can only be converted... So when you squeeze the bulb on a blood pressure cuff, you are applying kinetic energy. Then the cuff fills with...
How does momentum, inertia and drag affect the motion of an object?
10 hours ago How does momentum and inertia affect changes in speed, when considering acceleration from thrust, or from decelleration from drag? Say, for a...
What is Time-Varying Voltage?
11 hours ago In circuits, we have no problem saying that the voltage difference between two point is [itex]\cos(\omega t)[/itex], but what does that actually...
Contextual Relationships Between Momentum, Energy, and Force.
13 hours ago *I apologize in advance for the length of this post, if you wish to reduce reading skip to paragraph 5. Or if you are super lazy, the final...
Barometric pressure and the math behind it. Very interesting, I think.
14 hours ago Hey guys, I was actually researching the life of Edmond Halley and discovered that he discovered the relationship between barometric pressure and the...
- More from Physics Forums - Classical Physics
More news stories
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...
Immunology May 16, 2013 | 4.8 / 5 (5) | 0 |
Researchers from CNRS, Université Toulouse III - Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 ...
Immunology May 16, 2013 | not rated yet | 0
Women's immune systems age more slowly than men's, suggests research in BioMed Central's open access journal Immunity & Ageing. The slower decline in a woman's immune system may contribute to women living longer than men. ...
Immunology May 14, 2013 | not rated yet | 0
Newly described type of immune cell and T cells share similar path to maturity, according to new study
(Medical Xpress)—Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells (ILCs). Some researchers liken them to foot soldiers that ...
Immunology May 14, 2013 | 5 / 5 (3) | 0 |
(Medical Xpress)—Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory ...
Immunology May 13, 2013 | 5 / 5 (1) | 0 |
Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.
6 hours ago | 5 / 5 (1) | 0
For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests
Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...
7 hours ago | not rated yet | 0 |
(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...
19 hours ago | 3.7 / 5 (3) | 0 |
The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...
18 hours ago | not rated yet | 0 |
In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...
16 hours ago | 3.7 / 5 (3) | 0 |