Injecting botox into stomach does not promote weight loss

Despite conflicting data in support of the practice, some overweight Americans looking for an easy fix have turned to gastric botox injections to help them lose weight. This month in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association, researchers from the Mayo Clinic publish a definitive study finding that Botox doesn't promote weight loss.

Injecting A (BTA), or Botox, into the stomach had been believed to delay emptying of the stomach, increase feelings of fullness and reduce body weight. Researchers enrolled 60 in a 24-week, double-blind, randomized, placebo-controlled, concealed allocation trial to compare the effects of BTA to placebo. They found that the injection slowed movement of food through the stomach but it did not cause weight loss.

"On the basis of our findings, I would not recommend gastric to people who want to lose weight. There are some risks with this treatment and we found that there was no benefit in terms of body weight loss," said Mark Topazian, lead author of the study and professor of medicine in the Department of Gastroenterology and Hepatology at the Mayo Clinic, Rochester, MN.

A previous study had indicated that Botox was a promising weight loss option. This study invalidates those findings because it is larger, used ultrasound to ensure injections were properly placed, and limited bias by ensuring that neither physicians nor patients knew who received Botox and who received placebo injections.

"Unless future studies show different results I'd advise patients to seek other means of achieving weight loss," said Dr. Topazian.

add to favorites email to friend print save as pdf

Related Stories

Botox reduces wrinkles even in less frequent doses

Apr 26, 2010

Patients can decrease the frequency of Botox Cosmetic injections after approximately two years and still receive most of the same wrinkle-smoothing cosmetic benefits, according to new research at Oregon Health & Science University.

Don't let botox go to your head…or should you?

Jan 08, 2013

Injecting botox into the arm muscles of stroke survivors, with severe spasticity, changes electrical activity in the brain and may assist with longer-term recovery, according to new research.

Botox to iron out Australian asthma wrinkles

Jun 28, 2011

It is more celebrity than respiratory, but botox could prove a breath of fresh air for asthmatics if an Australian trial of the toxin launched Tuesday is successful.

Recommended for you

Schumacher's doctor sees progress after injury

5 hours ago

A French physician who treated Michael Schumacher for nearly six months after the Formula One champion struck his head in a ski accident says he is no longer in a coma and predicted a possible recovery within three years.

New MCAT shifts focus, will include humanities

Oct 20, 2014

(HealthDay)—The Medical College Admission Test (MCAT) has been revised, and the latest changes, including more humanities such as social sciences, are due to be implemented next April, according to a report ...

User comments