Don't let botox go to your head…or should you?

Dr. William Huynh.

Injecting botox into the arm muscles of stroke survivors, with severe spasticity, changes electrical activity in the brain and may assist with longer-term recovery, according to new research.

Researchers at NeuRA ( Australia) monitored nerve activity in the arms and brains of before and after botulinum toxin (botox) injections in rigid and stiff muscles in the arm.

They found that botox indeed improved arm muscles, but also altered in the cortex – the brain region responsible for movement, memory, learning and thinking.

" is used to treat a range of muscular and neurological conditions and our data shows that this treatment results in electrical and functional changes within the brain itself", says Dr William Huynh, lead author of the study and a research neurologist at NeuRA.

"This effect of botox on the brain may arise because the toxin travels to the central nervous system directly, or because muscles treated with botox are sending different signals back to the brain".

"Either way, we found that botox treatment in affected muscles not only improves muscle disorders in stroke patients, but also normalises electrical activity in the brain, particularly in the half of the brain not damaged by stroke".

"Restoring normal activity in the unaffected side of the brain is particularly important because we suspect that abnormal information sent from affected muscles to the brain may be disrupting patients' long-term recovery", Dr Huynh concluded.

This paper is published in the journal Muscle and Nerve.

More information: onlinelibrary.wiley.com/doi/10… 2/mus.23719/abstract

add to favorites email to friend print save as pdf

Related Stories

New insights about Botulinum toxin A

Dec 02, 2010

A new study by researchers at the Faculty of Kinesiology, University of Calgary, is raising questions about the therapeutic use of botulinum toxin A.

Botox to iron out Australian asthma wrinkles

Jun 28, 2011

It is more celebrity than respiratory, but botox could prove a breath of fresh air for asthmatics if an Australian trial of the toxin launched Tuesday is successful.

Australians trial Botox to treat hay fever

Oct 09, 2012

The best-selling wrinkle erasing drug Botox will be used in an Australian study to treat hay fever, researchers said Tuesday after it showed promise in providing relief in early trials.

US approves Botox for bladder control

Aug 24, 2011

The face-freezing pharmaceutical injection Botox gained another medical use on Wednesday when the US government approved it for use in some patients with overactive bladder.

Recommended for you

New viral tools for mapping brains

6 hours ago

(Medical Xpress)—A brain-computer-interphase that is optogenetically-enabled is one of the most fantastic technologies we might envision today. It is likely that its full power could only be realized under ...

Link seen between seizures and migraines in the brain

22 hours ago

Seizures and migraines have always been considered separate physiological events in the brain, but now a team of engineers and neuroscientists looking at the brain from a physics viewpoint discovered a link ...

Neuroscience: Why scratching makes you itch more

Oct 30, 2014

Turns out your mom was right: Scratching an itch only makes it worse. New research from scientists at Washington University School of Medicine in St. Louis indicates that scratching causes the brain to release ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.